Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30725769 | 1.00 | HIF1A (0.53) | HIF1ALMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30725768 | 0.86 | CYP1A2 (0.50) | HIF1ALMNAMEN1KMT2AMAPT | |
| SCHEMBL28700972 | 0.86 | CYP1A2 (0.50) | HIF1ALMNAMEN1KMT2AMAPT | |
| SCHEMBL5214272 | 0.75 | CKS1B (0.49) | HIF1AGAAUSP2CYP1A2CYP3A4 | |
| SCHEMBL27878227 | 0.73 | AKT1 (0.47) | HIF1AMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL13657976 | 0.73 | SMN1; SMN2 (0.57) | LMNAMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL29580298 | 0.73 | CXCR4 (0.74) | HIF1ALMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28697301 | 0.73 | CKS1B (0.55) | HIF1ALMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30725763 | 0.73 | CKS1B (0.55) | HIF1ALMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5211084 | 0.70 | CKS1B (0.53) | LMNAMEN1KMT2ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118206499-A | 2,3, 5-Trisubstituted pyrazine compound and preparation method and application thereof | 郑州大学 | 2024-06-18 | — | — | CN | disclosed |
| CN-118146165-A | 2,3, 5-Trisubstituted pyrazine compound and preparation method and application thereof | 郑州大学 | 2024-06-07 | — | — | CN | disclosed |
| CN-113968824-B | 2,3, 5-trisubstituted pyrazine compound and preparation method and application thereof | 郑州大学 | 2024-01-19 | — | — | CN | disclosed |
| CN-113968824-A | 2,3, 5-trisubstituted pyrazine compound and preparation method and application thereof | 郑州大学 | 2022-01-25 | — | — | CN | disclosed |