Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 9/20 | 0.46 |
| ▸ | JAK2 | O60674 | 7/20 | 0.46 |
| ▸ | JAK1 | P23458 | 7/20 | 0.46 |
| ▸ | TYK2 | P29597 | 7/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.36 |
| ▸ | PIM1 | P11309 | 3/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.36 |
| ▸ | GSK3B | P49841 | 3/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.36 |
| ▸ | SGK1 | O00141 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20699403 | 0.93 | JAK3 (0.49) | JAK3JAK2JAK1TYK2FGFR1 | |
| SCHEMBL30161719 | 0.93 | JAK3 (0.49) | JAK3JAK2JAK1TYK2FGFR1 | |
| Trifluoroacetic Acid SCHEMBL28680413 | 0.89 | PIK3CD (0.45) | JAK3JAK2JAK1TYK2FGFR1 | |
| Trifluoroacetic Acid SCHEMBL29608317 | 0.89 | PIK3CD (0.45) | JAK3JAK2JAK1TYK2FGFR1 | |
| Trifluoroacetic Acid SCHEMBL28687582 | 0.85 | FGFR1 (0.42) | JAK3JAK2JAK1TYK2FGFR1 | |
| Trifluoroacetic Acid SCHEMBL28689763 | 0.84 | JAK3 (0.52) | JAK3JAK2JAK1TYK2 | |
| Trifluoroacetic Acid SCHEMBL28681300 | 0.83 | PIM1 (0.35) | JAK3JAK2JAK1TYK2PIK3CD | |
| Trifluoroacetic Acid SCHEMBL28686997 | 0.81 | JAK3 (0.47) | JAK3JAK2JAK1TYK2FGFR1 | |
| Trifluoroacetic Acid SCHEMBL29607193 | 0.80 | JAK2 (0.43) | JAK3JAK2JAK1TYK2FGFR1 | |
| SCHEMBL20699367 | 0.80 | PIK3CD (0.47) | JAK3JAK2JAK1TYK2FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113831326-A | Condensed heterocyclic derivative and application thereof in medicine | 四川海思科制药有限公司 | 2021-12-24 | — | — | CN | disclosed |