Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 11/20 | 0.47 |
| ▸ | JAK2 | O60674 | 9/20 | 0.47 |
| ▸ | JAK1 | P23458 | 9/20 | 0.47 |
| ▸ | TYK2 | P29597 | 9/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 3/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28931797 | 0.92 | JAK3 (0.51) | JAK3JAK2JAK1TYK2FGFR1 | |
| Trifluoroacetic Acid SCHEMBL28687582 | 0.90 | FGFR1 (0.42) | JAK3JAK2JAK1TYK2FGFR1 | |
| Trifluoroacetic Acid SCHEMBL29608317 | 0.87 | PIK3CD (0.45) | JAK3JAK2JAK1TYK2FGFR1 | |
| Trifluoroacetic Acid SCHEMBL28680413 | 0.87 | PIK3CD (0.45) | JAK3JAK2JAK1TYK2FGFR1 | |
| Trifluoroacetic Acid SCHEMBL28681300 | 0.85 | PIM1 (0.35) | JAK3JAK2JAK1TYK2PIK3CD | |
| SCHEMBL28689643 | 0.82 | FGFR1 (0.48) | JAK3JAK2JAK1TYK2FGFR1 | |
| Trifluoroacetic Acid SCHEMBL28689763 | 0.81 | JAK3 (0.52) | JAK3JAK2JAK1TYK2 | |
| Trifluoroacetic Acid SCHEMBL28686999 | 0.81 | JAK3 (0.46) | JAK3JAK2JAK1TYK2FGFR1 | |
| SCHEMBL28673136 | 0.80 | JAK3 (0.49) | JAK3JAK2JAK1TYK2FGFR1 | |
| SCHEMBL20699367 | 0.78 | PIK3CD (0.47) | JAK3JAK2JAK1TYK2FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113831326-A | Condensed heterocyclic derivative and application thereof in medicine | 四川海思科制药有限公司 | 2021-12-24 | — | — | CN | disclosed |