Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689211 | 0.89 | POLB (0.58) | POLBL3MBTL1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL15224114 | 0.86 | POLB (0.68) | POLBL3MBTL1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL2535206 | 0.86 | POLB (0.63) | POLBL3MBTL1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL27908646 | 0.85 | POLB (0.70) | POLBL3MBTL1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL10091153 | 0.82 | POLB (0.51) | POLBL3MBTL1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL28689531 | 0.81 | KMT2A (0.58) | POLBL3MBTL1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL28749374 | 0.81 | POLB (0.50) | POLBL3MBTL1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL1677341 | 0.81 | ELANE (0.58) | POLBL3MBTL1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL11034495 | 0.80 | POLB (0.59) | POLBL3MBTL1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL10091197 | 0.79 | POLB (0.48) | POLBL3MBTL1KMT2AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555573-A | Prostaglandin E2(PGE2)EP4Receptor antagonists | 多曼治疗学公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-113979977-A | Hexa-membered oxygen heterocyclic compound and synthetic method thereof | 上海麦克林生化科技有限公司 | 2022-01-28 | — | — | CN | disclosed |