Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28749442 | 0.83 | MEN1 (0.47) | POLBL3MBTL1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28688381 | 0.81 | POLB (0.51) | POLBL3MBTL1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL1677341 | 0.80 | ELANE (0.58) | POLBL3MBTL1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL28749468 | 0.78 | ALDH1A1 (0.54) | POLBKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL4120652 | 0.75 | POLB (0.58) | POLBL3MBTL1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL28749527 | 0.74 | KMT2A (0.58) | POLBL3MBTL1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL29237307 | 0.73 | POLB (0.46) | POLBL3MBTL1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL8316646 | 0.73 | POLB (0.63) | POLBL3MBTL1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL31501221 | 0.72 | L3MBTL1 (0.59) | POLBL3MBTL1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL27947134 | 0.72 | LMNA (0.61) | POLBL3MBTL1KMT2AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555573-A | Prostaglandin E2(PGE2)EP4Receptor antagonists | 多曼治疗学公司 | 2022-05-27 | — | — | CN | disclosed |