Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 8/20 | 0.62 |
| ▸ | PAK4 | O96013 | 2/20 | 0.51 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.51 |
| ▸ | PAK2 | Q13177 | 1/20 | 0.51 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.51 |
| ▸ | PAK6 | Q9NQU5 | 1/20 | 0.51 |
| ▸ | PAK5 | Q9P286 | 1/20 | 0.51 |
| ▸ | MAP3K14 | Q99558 | 11/20 | 0.50 |
| ▸ | CDK2 | P24941 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24153194 | 0.86 | CDC7 (0.60) | CDC7PAK4PAK1PAK2PKN1 | |
| SCHEMBL1613483 | 0.82 | MAP3K14 (0.48) | CDC7PAK4PAK1PAK2PKN1 | |
| SCHEMBL16610251 | 0.80 | TTBK1 (0.63) | CDC7MAP3K14CDK2 | |
| SCHEMBL1613155 | 0.79 | PAK4 (0.53) | CDC7PAK4PAK1PAK2PKN1 | |
| SCHEMBL28686987 | 0.77 | TTBK1 (0.63) | CDC7PAK4PAK1PAK2PKN1 | |
| SCHEMBL28664146 | 0.77 | PAK4 (0.53) | CDC7PAK4PAK1PAK2PKN1 | |
| SCHEMBL28675675 | 0.77 | PAK4 (0.62) | CDC7PAK4PAK1PAK2PKN1 | |
| SCHEMBL1613992 | 0.76 | PAK4 (0.46) | CDC7PAK4PAK1PAK2PKN1 | |
| SCHEMBL11970509 | 0.76 | PAK4 (0.63) | CDC7PAK4PAK1PAK2PKN1 | |
| SCHEMBL1613551 | 0.76 | PAK4 (0.55) | CDC7PAK4PAK1PAK2PKN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113831325-A | Novel indole derivatives, and preparation method and application thereof | 沈阳药科大学 | 2021-12-24 | — | — | CN | claimed |
| CN-113831325-A | Novel indole derivatives, and preparation method and application thereof | 沈阳药科大学 | 2021-12-24 | — | — | CN | disclosed |