Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22638960 | 0.85 | ACHE (0.45) | HTTLMNAHSD17B10ALDH1A1KDM4E | |
| SCHEMBL20455726 | 0.83 | TP53 (0.41) | HTTLMNAHSD17B10ALDH1A1KDM4E | |
| SCHEMBL22638948 | 0.80 | TSHR (0.42) | MEN1KMT2AACHEHDAC1HDAC3 | |
| SCHEMBL20470207 | 0.79 | HTT (0.43) | HTTLMNAHSD17B10ALDH1A1KDM4E | |
| SCHEMBL5447122 | 0.77 | HDAC3 (0.39) | LMNAMEN1KMT2AHDAC1HDAC3 | |
| SCHEMBL21551266 | 0.76 | HTT (0.48) | HTTLMNAHSD17B10ALDH1A1KDM4E | |
| SCHEMBL26077299 | 0.76 | HTT (0.48) | HTTLMNAHSD17B10ALDH1A1KDM4E | |
| SCHEMBL3132717 | 0.75 | HTT (0.53) | HTTLMNAHSD17B10ALDH1A1KDM4E | |
| SCHEMBL22638949 | 0.74 | KMT2A (0.38) | LMNAMEN1KMT2ATSHRCYP3A4 | |
| SCHEMBL28543980 | 0.74 | ACHE (0.44) | HTTLMNAHSD17B10ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113767092-B | Di-heterocyclic carbonyl substituted dihydropyrazoles, their preparation and their use in medicine | 劲方医药科技(上海)有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-113767092-A | Bis-heterocyclic carbonyl substituted dihydropyrazole compound, preparation method and medical application thereof | 劲方医药科技(上海)有限公司 | 2021-12-07 | — | — | CN | disclosed |