Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28684427 | 0.86 | POLB (0.55) | POLBFGFR1CYP2A6HDAC1APAF1 | |
| SCHEMBL13931440 | 0.84 | HDAC1 (0.50) | MTNR1AMTNR1BTDP1FGFR1CYP2A6 | |
| SCHEMBL5695756 | 0.81 | HDAC1 (0.48) | FGFR1CYP2A6HDAC1MEN1KMT2A | |
| SCHEMBL5695731 | 0.81 | MEN1 (0.57) | GRIN2BMTNR1AMTNR1BTDP1FGFR1 | |
| SCHEMBL4247958 | 0.81 | HDAC1 (0.39) | POLBMTNR1AMTNR1BTDP1FGFR1 | |
| SCHEMBL18250719 | 0.80 | POLB (0.46) | POLBGRIN2BMTNR1AMTNR1BTDP1 | |
| SCHEMBL18250323 | 0.78 | POLB (0.42) | POLBGRIN2BMTNR1AMTNR1BTDP1 | |
| SCHEMBL4242652 | 0.77 | LMNA (0.53) | MTNR1AMTNR1BTDP1FGFR1CYP2A6 | |
| SCHEMBL3414135 | 0.77 | HDAC1 (0.53) | TDP1FGFR1HDAC1MEN1KMT2A | |
| SCHEMBL19553517 | 0.76 | POLB (0.40) | POLBGRIN2BMTNR1AMTNR1BTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311882-B | Adenine derivatives as protein kinase inhibitors | BCI制药公司 | 2022-02-11 | — | — | CN | disclosed |