Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 13/20 | 0.72 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.53 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31457627 | 1.00 | ENPP1 (0.72) | ENPP1MTNR1BKITPDGFRBUSP2 | |
| SCHEMBL28931602 | 0.93 | ENPP1 (0.61) | ENPP1MTNR1BKITPDGFRB | |
| SCHEMBL22455020 | 0.87 | ENPP1 (0.71) | ENPP1MAPK1 | |
| SCHEMBL22441577 | 0.85 | ENPP1 (0.52) | ENPP1MTNR1BCYP3A4ALDH1A1LMNA | |
| SCHEMBL28689284 | 0.85 | ENPP1 (0.56) | ENPP1MTNR1BKITPDGFRBUSP2 | |
| SCHEMBL20782514 | 0.84 | ENPP1 (1.00) | ENPP1MTNR1B | |
| SCHEMBL22455035 | 0.83 | ENPP1 (0.66) | ENPP1PDGFRBMAPK1 | |
| SCHEMBL31457626 | 0.80 | ENPP1 (0.48) | ENPP1ALDH1A1MEN1KMT2A | |
| SCHEMBL22441609 | 0.80 | ENPP1 (0.48) | ENPP1ALDH1A1MEN1KMT2A | |
| SCHEMBL24391547 | 0.78 | ENPP1 (0.82) | ENPP1MTNR1BKITPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113924092-A | Quinoline and quinazoline compounds and methods of use thereof | 斯汀格瑞治疗股份有限公司 | 2022-01-11 | — | — | CN | disclosed |