Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 13/20 | 0.61 |
| ▸ | KIT | P10721 | 2/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28689286 | 0.93 | ENPP1 (0.72) | ENPP1KITPDGFRBMTNR1B | |
| SCHEMBL31457627 | 0.93 | ENPP1 (0.72) | ENPP1KITPDGFRBMTNR1B | |
| SCHEMBL22455020 | 0.87 | ENPP1 (0.71) | ENPP1PDE10A | |
| SCHEMBL31457626 | 0.85 | ENPP1 (0.48) | ENPP1ENPP3 | |
| SCHEMBL22441609 | 0.85 | ENPP1 (0.48) | ENPP1ENPP3 | |
| SCHEMBL28931601 | 0.85 | ENPP1 (0.47) | ENPP1KITPDGFRBMTNR1BPDE3B | |
| SCHEMBL22407460 | 0.84 | ENPP1 (0.85) | ENPP1 | |
| SCHEMBL22455035 | 0.83 | ENPP1 (0.66) | ENPP1PDGFRBPDE10A | |
| SCHEMBL24391962 | 0.81 | ENPP1 (0.68) | ENPP1KITPDGFRBMTNR1BPDE3B | |
| SCHEMBL22441577 | 0.80 | ENPP1 (0.52) | ENPP1MTNR1BENPP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113924092-B | Quinoline and quinazoline compounds and methods of use thereof | 斯汀格瑞治疗股份有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-113924092-A | Quinoline and quinazoline compounds and methods of use thereof | 斯汀格瑞治疗股份有限公司 | 2022-01-11 | — | — | CN | disclosed |