Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 12/20 | 0.73 |
| ▸ | MEN1 | O00255 | 9/20 | 0.73 |
| ▸ | RAB9A | P51151 | 6/20 | 0.73 |
| ▸ | NPC1 | O15118 | 5/20 | 0.73 |
| ▸ | MAPT | P10636 | 11/20 | 0.55 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 8/20 | 0.53 |
| ▸ | POLB | P06746 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | NSD2 | O96028 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | CASP6 | P55212 | 2/20 | 0.53 |
| ▸ | ALPL | P05186 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28330096 | 0.87 | KMT2A (0.69) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL28328809 | 0.86 | KMT2A (0.65) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL2466702 | 0.85 | NPC1 (0.71) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL14788069 | 0.85 | NPC1 (0.71) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL28827217 | 0.82 | MAPT (0.62) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL1132698 | 0.82 | MEN1 (0.75) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL22261609 | 0.82 | MAPT (0.74) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL22261610 | 0.82 | MAPT (0.74) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL1132701 | 0.82 | MEN1 (0.75) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL30677901 | 0.82 | MAPT (0.74) | KMT2AMEN1RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110229081-B | 2, 4-dinitrophenylhydrazone derivative and preparation method and application thereof | 长沙理工大学 | 2022-02-08 | — | — | CN | disclosed |