Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 11/20 | 0.65 |
| ▸ | MEN1 | O00255 | 8/20 | 0.65 |
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 9/20 | 0.63 |
| ▸ | GAA | P10253 | 8/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 3/20 | 0.62 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | GFER | P55789 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | GSK3A | P49840 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.52 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28689490 | 0.86 | KMT2A (0.73) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL31329328 | 0.83 | MAPT (0.72) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL28330096 | 0.81 | KMT2A (0.69) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL28621063 | 0.80 | MAPT (0.56) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL28485506 | 0.80 | GSK3A (0.80) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL28827217 | 0.79 | MAPT (0.62) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL28510034 | 0.77 | GAA (0.79) | KMT2AMEN1MAPTGAAL3MBTL1 | |
| SCHEMBL15627358 | 0.77 | MAPT (0.53) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL22261609 | 0.76 | MAPT (0.74) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL22261610 | 0.76 | MAPT (0.74) | KMT2AMEN1RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110229081-B | 2, 4-dinitrophenylhydrazone derivative and preparation method and application thereof | 长沙理工大学 | 2022-02-08 | — | — | CN | claimed |
| CN-110229081-A | 2,4- dinitrobenzene hydazone derivative and the preparation method and application thereof | 长沙理工大学 | 2019-09-13 | — | — | CN | claimed |
| CN-115160180-A | Green synthesis method of vanillin shrinkage 2, 4-dinitrophenylhydrazone | 广东海洋大学 | 2022-10-11 | — | — | CN | disclosed |
| CN-110229081-B | 2, 4-dinitrophenylhydrazone derivative and preparation method and application thereof | 长沙理工大学 | 2022-02-08 | — | — | CN | disclosed |
| CN-110229081-A | 2,4- dinitrobenzene hydazone derivative and the preparation method and application thereof | 长沙理工大学 | 2019-09-13 | — | — | CN | disclosed |