Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 2/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.38 |
| ▸ | PRMT8 | Q9NR22 | 2/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25171934 | 0.85 | — | — | |
| SCHEMBL24307333 | 0.82 | ALDH1A1 (0.45) | CARM1PRMT6PRMT8PRMT1ALDH1A1 | |
| SCHEMBL17207595 | 0.82 | CARM1 (0.43) | CARM1PRMT6PRMT8PRMT1ALDH1A1 | |
| SCHEMBL10177623 | 0.81 | CARM1 (0.58) | CARM1PRMT6PRMT8PRMT1ALDH1A1 | |
| SCHEMBL17057349 | 0.80 | CARM1 (0.42) | CARM1PRMT6PRMT8PRMT1ALDH1A1 | |
| SCHEMBL17500346 | 0.80 | CARM1 (0.61) | CARM1PRMT6PRMT8PRMT1ALDH1A1 | |
| SCHEMBL12550917 | 0.79 | KDM4E (0.36) | ALDH1A1NPC1HPGDMEN1KMT2A | |
| SCHEMBL12550916 | 0.79 | KDM4E (0.36) | ALDH1A1NPC1HPGDMEN1KMT2A | |
| SCHEMBL12550915 | 0.79 | KDM4E (0.36) | ALDH1A1NPC1HPGDMEN1KMT2A | |
| SCHEMBL12550911 | 0.79 | KDM4E (0.36) | ALDH1A1NPC1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113195498-A | Novel imidazopyrazine derivatives | 豪夫迈·罗氏有限公司 | 2021-07-30 | — | — | CN | disclosed |