Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28689881 | 1.00 | SLC6A3 (0.47) | SLC6A3SLC6A2SLC6A4DHFR | |
| SCHEMBL16643913 | 1.00 | SLC6A3 (0.47) | SLC6A3SLC6A2SLC6A4DHFR | |
| SCHEMBL21370432 | 1.00 | SLC6A3 (0.47) | SLC6A3SLC6A2SLC6A4DHFR | |
| SCHEMBL17337683 | 0.86 | SLC6A3 (0.46) | SLC6A3SLC6A2SLC6A4DHFR | |
| SCHEMBL15292983 | 0.86 | SLC6A3 (0.46) | SLC6A3SLC6A2SLC6A4DHFR | |
| SCHEMBL23987692 | 0.86 | SLC6A3 (0.46) | SLC6A3SLC6A2SLC6A4DHFR | |
| SCHEMBL17337681 | 0.86 | SLC6A3 (0.46) | SLC6A3SLC6A2SLC6A4DHFR | |
| SCHEMBL19303675 | 0.82 | SLC6A3 (0.51) | SLC6A3SLC6A2SLC6A4DHFR | |
| SCHEMBL17337527 | 0.81 | SLC6A3 (0.40) | SLC6A3SLC6A2SLC6A4DHFR | |
| SCHEMBL17337530 | 0.81 | SLC6A3 (0.40) | SLC6A3SLC6A2SLC6A4DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114025795-A | Methods of treating biliary tract cancer using bispecific antigen-binding constructs targeting HER2 | 酵活有限公司 | 2022-02-08 | — | — | CN | disclosed |