Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.91 |
| ▸ | TP53 | P04637 | 4/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.71 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28932883 | 0.96 | MAPT (1.00) | MAPTTP53ALDH1A1LMNAGAA | |
| SCHEMBL28703720 | 0.92 | MAPT (0.93) | MAPTTP53ALDH1A1LMNAGAA | |
| SCHEMBL28703726 | 0.92 | MAPT (0.93) | MAPTTP53ALDH1A1LMNAGAA | |
| SCHEMBL4596903 | 0.91 | MAPT (0.75) | MAPTTP53ALDH1A1SCN9AL3MBTL1 | |
| SCHEMBL28693188 | 0.91 | ALDH1A1 (0.77) | MAPTTP53ALDH1A1LMNASCN9A | |
| SCHEMBL28932882 | 0.90 | MAPT (0.89) | MAPTTP53ALDH1A1LMNAGAA | |
| SCHEMBL28703794 | 0.89 | MAPT (0.88) | MAPTTP53ALDH1A1LMNAGAA | |
| SCHEMBL4597501 | 0.89 | MAPT (0.72) | MAPTTP53ALDH1A1LMNAGAA | |
| SCHEMBL28683361 | 0.88 | MAPT (0.84) | MAPTTP53ALDH1A1LMNAGAA | |
| SCHEMBL28703749 | 0.88 | MAPT (0.84) | MAPTTP53ALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057626-A | Indole-2, 3-dione derivative, preparation method thereof and anti-liver cancer drug for inhibiting RECQL4 specific expression | 山东第一医科大学(山东省医学科学院) | 2022-02-18 | — | — | CN | disclosed |