SCHEMBL28690459

SCHEMBL28690459

COC(=O)c1ccc(NS(C)(=O)=O)cc1S(=O)(=O)Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.52
SMN1; SMN2 Q16637 3/20 0.51
KDM4E B2RXH2 1/20 0.51
HSD17B10 Q99714 1/20 0.51
CHEK1 O14757 1/20 0.48
AURKA O14965 1/20 0.48
DAPK3 O43293 1/20 0.48
JAK2 O60674 1/20 0.48
ABL1 P00519 1/20 0.48
NTRK1 P04629 1/20 0.48
FYN P06241 1/20 0.48
CSF1R P07333 1/20 0.48
RET P07949 1/20 0.48
IGF1R P08069 1/20 0.48
MET P08581 1/20 0.48
PDGFRB P09619 1/20 0.48
PIM1 P11309 1/20 0.48
FGFR1 P11362 1/20 0.48
PRKACA P17612 1/20 0.48
LTK P29376 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28341785 0.84 POLB (0.51) POLBSMN1; SMN2KDM4EHSD17B10CHEK1
SCHEMBL1016778 0.82 POLB (0.55) POLBSMN1; SMN2KDM4EHSD17B10CHEK1
SCHEMBL15754433 0.80 SMN1; SMN2 (0.62) POLBSMN1; SMN2KDM4EHSD17B10CHEK1
SCHEMBL5324234 0.80 KDM4E (0.59) POLBSMN1; SMN2KDM4EHSD17B10CHEK1
SCHEMBL26800515 0.79 KDM4E (0.57) POLBSMN1; SMN2KDM4EHSD17B10CHEK1
SCHEMBL7686884 0.79 POLB (0.55) POLBSMN1; SMN2KDM4EHSD17B10CHEK1
SCHEMBL22032826 0.79 LMNA (0.62) POLBSMN1; SMN2KDM4EHSD17B10CHEK1
SCHEMBL6152074 0.78 KDM4E (0.56) SMN1; SMN2KDM4EHSD17B10KDRHPGD
SCHEMBL5452555 0.78 ABL1 (0.58) POLBSMN1; SMN2KDM4EHSD17B10ABL1
SCHEMBL19194044 0.78 CA1 (0.46) SMN1; SMN2KDM4EHSD17B10ABL1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114133345-A Preparation method of 2-chlorosulfonyl-4-methanesulfonamide methyl benzoate 顺毅宜昌化工有限公司 2022-03-04 CN claimed
CN-114133345-A Preparation method of 2-chlorosulfonyl-4-methanesulfonamide methyl benzoate 顺毅宜昌化工有限公司 2022-03-04 CN disclosed
CN-114133345-A Preparation method of 2-chlorosulfonyl-4-methanesulfonamide methyl benzoate 顺毅宜昌化工有限公司 2022-03-04 CN disclosed
CN-114133345-A Preparation method of 2-chlorosulfonyl-4-methanesulfonamide methyl benzoate 顺毅宜昌化工有限公司 2022-03-04 CN disclosed