Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.49 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.49 |
| ▸ | ENPP3 | O14638 | 3/20 | 0.48 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28700605 | 1.00 | HPGD (0.60) | HPGDPTPN1ALDH1A1GRM4TSHR | |
| SCHEMBL28685818 | 0.99 | HPGD (0.57) | HPGDPTPN1ALDH1A1GRM4TSHR | |
| SCHEMBL28704844 | 0.96 | HPGD (0.54) | HPGDPTPN1ALDH1A1GRM4TSHR | |
| SCHEMBL28706297 | 0.93 | KMT2A (0.55) | HPGDPTPN1ALDH1A1TSHRMEN1 | |
| SCHEMBL28933271 | 0.82 | EPHX2 (0.64) | HPGDALDH1A1TSHRMEN1GFER | |
| SCHEMBL28691401 | 0.81 | EPHX2 (0.62) | HPGDMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL28691382 | 0.77 | EPHX2 (0.54) | HPGDALDH1A1GAAMAPTKMT2A | |
| SCHEMBL19703413 | 0.76 | HPGD (1.00) | HPGDPTPN1ALDH1A1KCNK3KCNK9 | |
| SCHEMBL1300190 | 0.76 | HPGD (1.00) | HPGDPTPN1ALDH1A1KCNK3KCNK9 | |
| SCHEMBL21653300 | 0.75 | PTPN1 (0.54) | HPGDPTPN1ALDH1A1ENPP3ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057630-B | Pirfenidone derivative and synthetic method and application thereof | 郑州大学 | 2023-06-02 | — | — | CN | claimed |
| CN-114057630-A | Pirfenidone derivative and synthetic method and application thereof | 郑州大学 | 2022-02-18 | — | — | CN | claimed |
| CN-114057630-B | Pirfenidone derivative and synthetic method and application thereof | 郑州大学 | 2023-06-02 | — | — | CN | disclosed |
| CN-114057630-A | Pirfenidone derivative and synthetic method and application thereof | 郑州大学 | 2022-02-18 | — | — | CN | disclosed |