SCHEMBL2869111

SCHEMBL2869111

CC(C)C[C@@H]1NC(=O)[C@H](C(C)C)NC1=O

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.39
MLNR O43193 2/20 0.39
MEN1 O00255 2/20 0.38
ALDH1A1 P00352 2/20 0.38
KMT2A Q03164 2/20 0.38
MAPT P10636 1/20 0.38
HDAC1 Q13547 2/20 0.37
ITGB1 P05556 6/20 0.36
ITGA4 P13612 6/20 0.36
ITGB2 P05107 5/20 0.36
ITGA1 P56199 4/20 0.36
ITGB7 P26010 3/20 0.36
GABRA4 P48169 3/20 0.36
ITGA5 P08648 2/20 0.36
ITGAM P11215 2/20 0.36
CTSD P07339 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30038822 1.00 HRH3 (0.39) HRH3MLNRMEN1ALDH1A1KMT2A
SCHEMBL30436539 1.00 HRH3 (0.39) HRH3MLNRMEN1ALDH1A1KMT2A
SCHEMBL6440744 1.00 HRH3 (0.39) HRH3MLNRMEN1ALDH1A1KMT2A
SCHEMBL29822681 0.93 MLNR (0.38) HRH3MLNRMEN1ALDH1A1KMT2A
Chrysosporide SCHEMBL30609551 0.91 ITGB1 (0.43) HRH3MLNRHDAC1ITGB1ITGA4
SCHEMBL29885671 0.90 PSMB11 (0.38) HRH3MLNRMEN1ALDH1A1KMT2A
SCHEMBL163425 0.87 MEN1 (0.41) MEN1KMT2A
SCHEMBL2867325 0.87 MEN1 (0.41) MEN1KMT2A
SCHEMBL14952770 0.85 MEN1 (0.33) MLNRMEN1ALDH1A1KMT2AMAPT
SCHEMBL6989670 0.84 HDAC3 (0.50) HRH3MLNRHDAC1ITGB1ITGA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1515684-B1 CARE AND/OR MAKE-UP COSMETIC COMPOSITION STRUCTURED WITH SILICONE POLYMERS AND ORGANOGELLING AGENTS, IN RIGID FORM OREAL (FR) 2010-05-19 EP claimed
US-20050245673-A1 Care and/or make-up cosmetic composition structured with silicone polymers and organogelling agents, in rigid form L'OREAL S.A. (FR) 2005-11-03 US claimed
US-10751495-B2 Patient interface KONINKLIJKE PHILIPS N.V. (NL) 2020-08-25 US disclosed
EP-3082924-B1 PATIENT INTERFACE KONINKLIJKE PHILIPS NV (NL) 2019-11-13 EP disclosed
US-9848600-B2 Biofilm disruptive compositions JOHNSON & JOHNSON CONSUMER INC. (US) 2017-12-26 US disclosed
US-9591852-B2 Biofilm disruptive compositions MCNEIL-PPC, INC. (US) 2017-03-14 US disclosed
US-20160317771-A1 PATIENT INTERFACE KONINKLIJKE PHILIPS N.V. 2016-11-03 US disclosed
US-20160317771-A1 PATIENT INTERFACE KONINKLIJKE PHILIPS N.V. 2016-11-03 US disclosed
WO-2015091304-A1 PATIENT INTERFACE KONINKLIJKE PHILIPS N.V. (NL) 2015-06-25 WO disclosed
US-7820146-B2 Care and/or make-up cosmetic composition structured with silicone polymers and organogelling agents, in rigid form L'OREAL S.A. (FR) 2010-10-26 US disclosed
EP-1515684-B1 CARE AND/OR MAKE-UP COSMETIC COMPOSITION STRUCTURED WITH SILICONE POLYMERS AND ORGANOGELLING AGENTS, IN RIGID FORM OREAL (FR) 2010-05-19 EP disclosed
US-20050245673-A1 Care and/or make-up cosmetic composition structured with silicone polymers and organogelling agents, in rigid form L'OREAL S.A. (FR) 2005-11-03 US disclosed
US-20050077648-A1 Solution casting method and polymer film FUJIFILM CORPORATION (JP) 2005-04-14 US disclosed