SCHEMBL163425

SCHEMBL163425

CC(C)CC1NC(=O)C(CC(C)C)NC1=O

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
GAA P10253 3/20 0.40
LMNA P02545 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
HTT P42858 2/20 0.38
PAX8 Q06710 1/20 0.38
PRCP P42785 1/20 0.32
GHSR Q92847 3/20 0.32
PDE5A O76074 1/20 0.32
SOAT2 O75908 1/20 0.32
SOAT1 P35610 1/20 0.32
VDR P11473 2/20 0.31
CCR5 P51681 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2867325 1.00 MEN1 (0.41) MEN1KMT2AGAALMNACYP3A4
SCHEMBL4404002 0.91 MEN1 (0.37) MEN1KMT2AGAALMNACYP3A4
SCHEMBL14952860 0.91 MEN1 (0.37) MEN1KMT2AGAALMNACYP3A4
SCHEMBL14952771 0.89 MEN1 (0.36) MEN1KMT2AGAALMNACYP3A4
SCHEMBL13033905 0.89 SOAT1 (0.40) MEN1KMT2AGAALMNACYP3A4
SCHEMBL30415527 0.89 SOAT1 (0.40) MEN1KMT2AGAALMNACYP3A4
SCHEMBL30038822 0.87 HRH3 (0.39) MEN1KMT2A
SCHEMBL6440744 0.87 HRH3 (0.39) MEN1KMT2A
SCHEMBL2869111 0.87 HRH3 (0.39) MEN1KMT2A
SCHEMBL30436539 0.87 HRH3 (0.39) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115536598-B New synthesis method of 1, 4-dimethyl-2, 5-piperazine dione compound 青岛科技大学 2024-04-02 CN claimed
CN-115536598-A Novel synthesis method of 1,4-dimethyl-2,5-piperazinedione compound 青岛科技大学 2022-12-30 CN claimed
US-9738685-B2 Use of ruthenium complexes for preparing amides, polypeptides and cyclic dipeptides YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2017-08-22 US claimed
WO-2010030197-A1 CONCENTRATION OF ALGAL BIOMASS MILLER IAN JAMES (NZ) 2010-03-18 WO claimed
CN-115536598-B New synthesis method of 1, 4-dimethyl-2, 5-piperazine dione compound 青岛科技大学 2024-04-02 CN disclosed
CN-115536598-A Novel synthesis method of 1,4-dimethyl-2,5-piperazinedione compound 青岛科技大学 2022-12-30 CN disclosed
EP-3443054-B1 PROCESS FOR PRODUCING A COMBUSTIBLE PRODUCT INDUSTRIAL CHEMICALS GROUP LTD (GB) 2020-01-29 EP disclosed
EP-2629889-B1 RUTHENIUM COMPLEXES AND THEIR USES IN PROCESSES FOR FORMATION AND/OR HYDROGENATION OF ESTERS, AMIDES AND DERIVATIVES THEREOF YEDA RES & DEV (IL) 2019-04-03 EP disclosed
EP-2629889-B1 RUTHENIUM COMPLEXES AND THEIR USES IN PROCESSES FOR FORMATION AND/OR HYDROGENATION OF ESTERS, AMIDES AND DERIVATIVES THEREOF YEDA RES & DEV (IL) 2019-04-03 EP disclosed
US-9840479-B2 Polyamine-fatty acid derived lipidoids and uses thereof MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2017-12-12 US disclosed
EP-3231856-A1 COMBUSTIBLE PRODUCT Industrial Chemicals Group Limited (GB) 2017-10-18 EP disclosed
US-9738685-B2 Use of ruthenium complexes for preparing amides, polypeptides and cyclic dipeptides YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2017-08-22 US disclosed
US-20110295006-A1 CYCLIC DIPEPTIDES AS FEED ADDITIVES EVONIK DEGUSSA GMBH (DE) 2011-12-01 US disclosed
WO-2011126383-A1 HYDROTHERMAL TRANSFORMATION OF MICROALGAE THROUGH CATALYSIS WITH CLAYS AND ALUMINOSILICATES AQUAFLOW BIONOMIC CORPORATION LIMITED (NZ) 2011-10-13 WO disclosed
WO-2011126382-A1 HYDROTHERMAL TRANSFORMATION OF MICROALGAE THROUGH METAL-BASE CATALYSIS AQUAFLOW BIONOMIC CORPORATION LIMITED (NZ) 2011-10-13 WO disclosed
US-20110232344-A1 CONCENTRATION OF ALGAL BIOMASS AQUAFLOW BIONOMIC CORPORATION LIMITED (NZ) 2011-09-29 US disclosed
US-7745392-B2 Multi-valent guanidinium compounds for enhancing molecular translocation across cellular membranes and epithelial tissues NITTO DENKO CORPORATION (JP) 2010-06-29 US disclosed
WO-2010030197-A1 CONCENTRATION OF ALGAL BIOMASS MILLER IAN JAMES (NZ) 2010-03-18 WO disclosed
US-20070078078-A1 Multi-valent guanidinium compounds for enhancing molecular translocation across cellular membranes and epithelial tissues NITTO DENKO CORPORATION (JP) 2007-04-05 US disclosed
US-20050077648-A1 Solution casting method and polymer film FUJIFILM CORPORATION (JP) 2005-04-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110295006-A1 CYCLIC DIPEPTIDES AS FEED ADDITIVES VIP, AADAT, ARGLU1 MEN1 2911/4885KMT2A 1037/4885GAA 4782/4885
US-20070078078-A1 Multi-valent guanidinium compounds for enhancing molecular translocation across cellular membranes and epithelial tissues GLS, FABP2, GOLIM4 MEN1 4047/4885KMT2A 4516/4885GAA 263/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.