Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 4/20 | 0.38 |
| ▸ | CES1 | P23141 | 4/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL28709202 | 0.91 | TSHR (0.40) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL4576740 | 0.85 | TSHR (0.40) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL4577209 | 0.82 | TSHR (0.50) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28703476 | 0.82 | TSHR (0.50) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL1784685 | 0.81 | TSHR (0.45) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28701822 | 0.81 | DAO (0.48) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL27573803 | 0.80 | TSHR (0.44) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL1786441 | 0.80 | DAO (0.44) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL4837242 | 0.80 | DAO (0.47) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28698367 | 0.80 | DAO (0.47) | TSHRDAONAPRTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114085301-B | Solid catalyst component for preparing olefin polymer and application thereof | 中国石油化工股份有限公司 | 2023-05-09 | — | — | CN | claimed |
| CN-114085301-A | Solid catalyst component for preparing olefin polymer and application thereof | 中国石油化工股份有限公司 | 2022-02-25 | — | — | CN | claimed |
| CN-114085301-B | Solid catalyst component for preparing olefin polymer and application thereof | 中国石油化工股份有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-114085301-A | Solid catalyst component for preparing olefin polymer and application thereof | 中国石油化工股份有限公司 | 2022-02-25 | — | — | CN | disclosed |