Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28692005 | 1.00 | KRAS (0.55) | KRAS | |
| SCHEMBL22720273 | 0.88 | KRAS (0.52) | KRAS | |
| SCHEMBL30825296 | 0.88 | KRAS (0.52) | KRAS | |
| SCHEMBL22724649 | 0.88 | KRAS (0.52) | KRAS | |
| SCHEMBL21733988 | 0.87 | KRAS (0.68) | KRAS | |
| SCHEMBL21722172 | 0.87 | KRAS (0.68) | KRAS | |
| SCHEMBL30178152 | 0.87 | KRAS (0.68) | KRAS | |
| SCHEMBL21722155 | 0.86 | KRAS (0.52) | KRAS | |
| SCHEMBL22720277 | 0.85 | KRAS (0.49) | KRAS | |
| SCHEMBL28710948 | 0.82 | KRAS (0.46) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113396147-B | Aromatic heterocyclic derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-113396147-A | Aromatic heterocyclic derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2021-09-14 | — | — | CN | disclosed |