Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | KIF5B | P33176 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.31 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28692115 | 1.00 | HTR2A (0.41) | HTR2ASLC6A4SCN9ATSHRDRD4 | |
| SCHEMBL22445376 | 0.90 | ALDH1A1 (0.41) | HTR2ASLC6A4SCN9ATSHRDRD4 | |
| SCHEMBL22445377 | 0.90 | ALDH1A1 (0.41) | HTR2ASLC6A4SCN9ATSHRDRD4 | |
| SCHEMBL26111042 | 0.77 | HTR2A (0.36) | HTR2ASLC6A4ALDH1A1SLC6A2HTR2B | |
| SCHEMBL10188111 | 0.69 | DRD4 (0.41) | HTR2ASLC6A4SCN9ATSHRDRD4 | |
| SCHEMBL22445367 | 0.68 | — | — | |
| SCHEMBL30140391 | 0.67 | HTR2A (0.37) | HTR2ASLC6A4SCN9ATSHRDRD4 | |
| SCHEMBL13696464 | 0.66 | ALDH1A1 (0.47) | HTR2ASLC6A4SCN9ADRD4ALDH1A1 | |
| SCHEMBL2834264 | 0.66 | SMN1; SMN2 (0.42) | TSHRDRD4ALDH1A1 | |
| SCHEMBL23847921 | 0.66 | EGLN2 (0.43) | HTR2ASLC6A4SCN9ATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114144230-B | Macrocyclic azolopyridine derivatives as EED and PRC2 modulators | 弗尔康医疗公司 | 2024-04-23 | — | — | CN | disclosed |
| CN-114144230-A | Macrocyclic azolopyridine derivatives as EED and PRC2 modulators | 弗尔康医疗公司 | 2022-03-04 | — | — | CN | disclosed |