Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MMP1 | P03956 | 4/20 | 0.49 |
| ▸ | MMP3 | P08254 | 4/20 | 0.49 |
| ▸ | MMP9 | P14780 | 4/20 | 0.49 |
| ▸ | MMP2 | P08253 | 3/20 | 0.49 |
| ▸ | MMP8 | P22894 | 3/20 | 0.49 |
| ▸ | MMP7 | P09237 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29482632 | 1.00 | MAPT (0.53) | MAPTSMN1; SMN2MEN1KMT2AMMP1 | |
| SCHEMBL28703410 | 0.91 | CYP2C9 (0.58) | MAPTSMN1; SMN2LMNACYP2C9ALDH1A1 | |
| SCHEMBL29482652 | 0.88 | LMNA (0.57) | MAPTSMN1; SMN2MEN1KMT2AMMP1 | |
| SCHEMBL28711508 | 0.88 | LMNA (0.57) | MAPTSMN1; SMN2MEN1KMT2AMMP1 | |
| SCHEMBL28711520 | 0.84 | LMNA (0.52) | MAPTSMN1; SMN2MEN1KMT2AMMP1 | |
| SCHEMBL29482633 | 0.84 | LMNA (0.52) | MAPTSMN1; SMN2MEN1KMT2AMMP1 | |
| SCHEMBL28712877 | 0.83 | LMNA (0.51) | MAPTMEN1KMT2AMMP1MMP3 | |
| SCHEMBL29482649 | 0.83 | LMNA (0.51) | MAPTMEN1KMT2AMMP1MMP3 | |
| SCHEMBL28702258 | 0.81 | LMNA (0.47) | MAPTMEN1KMT2AMMP1MMP3 | |
| SCHEMBL29482646 | 0.81 | LMNA (0.47) | MAPTMEN1KMT2AMMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114230529-A | Tetrahydroquinoxaline sulfonamide derivative and preparation method and application thereof | 河南大学 | 2022-03-25 | — | — | CN | disclosed |