SCHEMBL2869249

SCHEMBL2869249

C=C1CC(c2ccc(N(C)C)cc2)C(=O)C1c1ccc(N(C)C)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.41
ALOX15 P16050 4/20 0.41
RECQL P46063 1/20 0.41
MAPK1 P28482 3/20 0.39
POLB P06746 1/20 0.39
TSHR P16473 2/20 0.36
HSD17B10 Q99714 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
MAPT P10636 4/20 0.35
TDP1 Q9NUW8 2/20 0.34
TP53 P04637 1/20 0.34
CYP3A4 P08684 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
GAA P10253 2/20 0.33
KDM4E B2RXH2 1/20 0.33
HTT P42858 1/20 0.33
GFER P55789 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28745563 0.65 ALDH1A1 (0.44) ALDH1A1ALOX15RECQLMAPK1POLB
SCHEMBL22732966 0.64 ALDH1A1 (0.48) ALDH1A1ALOX15RECQLMAPK1TSHR
SCHEMBL30424074 0.64 METAP1 (0.49) ALDH1A1MAPK1POLBL3MBTL1MAPT
SCHEMBL4421610 0.63 MAPT (0.57) ALDH1A1ALOX15RECQLMAPK1POLB
SCHEMBL14087594 0.61 MEN1 (0.43) ALDH1A1ALOX15RECQLMAPK1TSHR
SCHEMBL427214 0.61 ESR2 (0.46) ALDH1A1ALOX15RECQLMAPK1TSHR
SCHEMBL427215 0.61 ESR2 (0.46) ALDH1A1ALOX15RECQLMAPK1TSHR
SCHEMBL15432765 0.60 MAPK1 (0.52) ALDH1A1ALOX15MAPK1POLBTSHR
SCHEMBL25340831 0.60 ALDH1A1 (0.48) ALDH1A1ALOX15RECQLMAPK1TSHR
SCHEMBL7002394 0.60 KDM1A (0.54) HSD17B10CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8431289-B2 Photosensitive composition for volume hologram recording, photosensitive medium for volume hologram recording and volume hologram DAI NIPPON PRINTING CO., LTD. (JP) 2013-04-30 US disclosed
US-7824822-B2 Photosensitive compositions for volume hologram recording, photosensitive medium for volume hologram recording and volume hologram DAI NIPPON PRINTING CO., LTD. (JP) 2010-11-02 US disclosed
US-20100266936-A1 PHOTOSENSITIVE COMPOSITION FOR VOLUME HOLOGRAM RECORDING, PHOTOSENSITIVE MEDIUM FOR VOLUME HOLOGRAM RECORDING AND VOLUME HOLOGRAM DAI NIPPON PRINTING CO., LTD. (JP) 2010-10-21 US disclosed
US-20040137334-A1 Volume hologram recording photosensitive composition, volume hologram recording photosensitive medium and volume hologram DAI NIPPON PRINTING CO., LTD. (JP) 2004-07-15 US disclosed