Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5744441 | 0.83 | TAAR1 (0.38) | KDM4ECYP3A4CYP2C19HIF1A | |
| SCHEMBL5742196 | 0.83 | CYP3A4 (0.34) | KDM4ECYP3A4CYP2C19HIF1A | |
| SCHEMBL2006566 | 0.80 | IDO1 (0.37) | KDM4ECYP3A4CYP2C19HIF1A | |
| SCHEMBL2877822 | 0.80 | IDO1 (0.37) | KDM4ECYP3A4CYP2C19HIF1A | |
| Hydrochloric Acid SCHEMBL2873715 | 0.79 | IDO1 (0.37) | KDM4ECYP3A4CYP2C19HIF1A | |
| Hydrochloric Acid SCHEMBL2873712 | 0.79 | IDO1 (0.37) | KDM4ECYP3A4CYP2C19HIF1A | |
| SCHEMBL5744782 | 0.79 | BACE1 (0.35) | KDM4ECYP3A4CYP2C19HIF1A | |
| SCHEMBL3603437 | 0.71 | CNR2 (0.31) | — | |
| SCHEMBL2873106 | 0.70 | ABCC9 (0.37) | KDM4ECYP3A4CYP2C19HIF1A | |
| SCHEMBL2014393 | 0.70 | ABCC9 (0.37) | KDM4ECYP3A4CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732929-B1 | TRICYCLIC BENZOPYRAN COMPOUND AS ANTI-ARRHYTHMIC AGENTS | NISSAN CHEMICAL IND LTD (JP) | 2010-10-20 | — | — | EP | disclosed |