Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12126890 | 0.87 | HTT (0.49) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL2867969 | 0.87 | HTT (0.49) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL5417803 | 0.87 | HTT (0.49) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL28676073 | 0.82 | MAPT (0.54) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL23030168 | 0.77 | HTT (0.49) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL16189751 | 0.77 | NPC1 (0.50) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL15618724 | 0.77 | HTT (0.49) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL15623485 | 0.77 | HTT (0.49) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL28998621 | 0.76 | HTT (0.48) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL4158338 | 0.75 | L3MBTL1 (0.38) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113816918-A | Preparation method of linezolid chloro-impurity | 江苏吴中医药集团有限公司 | 2021-12-21 | — | — | CN | disclosed |