Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21069710 | 0.92 | HPGD (0.49) | MEN1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL21069366 | 0.89 | NR1H2 (0.49) | MEN1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL28683476 | 0.87 | MEN1 (0.44) | MEN1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL30043531 | 0.86 | HPGD (0.46) | MEN1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL13452495 | 0.85 | NR1H2 (0.50) | MEN1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL23071051 | 0.85 | MAPT (0.44) | MEN1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL22650349 | 0.83 | NR1H2 (0.46) | MEN1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL31752290 | 0.83 | MEN1 (0.50) | MEN1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL31753756 | 0.83 | MEN1 (0.50) | MEN1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL1904787 | 0.83 | MEN1 (0.50) | MEN1ALDH1A1MAPTKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113943276-A | Nitrogen heterocyclic compound and application thereof | 武汉人福创新药物研发中心有限公司 | 2022-01-18 | — | — | CN | disclosed |