Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634196 | 0.92 | MEN1 (0.51) | NR1H2HPGDALDH1A1MEN1MAPT | |
| SCHEMBL13162270 | 0.92 | MEN1 (0.51) | NR1H2HPGDALDH1A1MEN1MAPT | |
| SCHEMBL4428890 | 0.92 | MEN1 (0.51) | NR1H2HPGDALDH1A1MEN1MAPT | |
| SCHEMBL2149045 | 0.91 | GPR119 (0.51) | HPGDKDM4EPKMGPR119RECQL | |
| SCHEMBL13452495 | 0.90 | NR1H2 (0.50) | NR1H2HPGDKDM4EPKMALDH1A1 | |
| SCHEMBL25153730 | 0.89 | NR1H2 (0.43) | NR1H2HPGDKDM4EPKMALDH1A1 | |
| SCHEMBL23585483 | 0.88 | NR1H2 (0.54) | NR1H2HPGDKDM4EPKMALDH1A1 | |
| SCHEMBL8260467 | 0.87 | NR1H2 (0.44) | NR1H2HPGDKDM4EPKMALDH1A1 | |
| SCHEMBL16892198 | 0.86 | NR1H2 (0.49) | NR1H2HPGDKDM4EPKMALDH1A1 | |
| SCHEMBL3435726 | 0.86 | NR1H2 (0.49) | NR1H2HPGDKDM4EPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200354359-A1 | INHIBITING (ALPHA-V)(BETA-6) INTEGRIN | MORPHIC THERAPEUTIC, INC. | 2020-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200354359-A1 | INHIBITING (ALPHA-V)(BETA-6) INTEGRIN | ITGB6, ITGA6, ITGAV | NR1H2 2488/4885HPGD 3060/4885KDM4E 3490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.