SCHEMBL28693380

SCHEMBL28693380

COc1ccc(C=CC(=O)OC([SiH3])(O[Si](C)(C)C)C(O[Si](C)(C)C)C(C)C)c(OC)c1OC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 1/20 0.46
CYP1A1 P04798 4/20 0.44
CYP1B1 Q16678 4/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2D6 P10635 2/20 0.44
CYP3A4 P08684 1/20 0.43
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
LMNA P02545 1/20 0.41
TP53 P04637 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CHRNA7 P36544 1/20 0.39
NFE2L2 Q16236 2/20 0.37
ALOX5 P09917 1/20 0.35
ABCB1 P08183 1/20 0.35
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
TRPM8 Q7Z2W7 1/20 0.34
CYP19A1 P11511 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4836334 0.89 ABCG2 (0.37) ABCG2CYP1A1CYP1B1CYP1A2CYP2D6
SCHEMBL6701256 0.83 KDM4E (0.45) ABCG2CYP1A1CYP1B1CYP1A2CYP2D6
SCHEMBL3246989 0.82 ABCG2 (0.48) ABCG2CYP1A1CYP1B1CYP1A2CYP2D6
SCHEMBL22500107 0.71 ABCG2 (0.59) ABCG2CYP1A1CYP1B1CYP1A2CYP2D6
SCHEMBL22500105 0.71 ABCG2 (0.59) ABCG2CYP1A1CYP1B1CYP1A2CYP2D6
SCHEMBL1883771 0.71 ABCG2 (0.62) ABCG2CYP1A1CYP1B1CYP1A2CYP2D6
SCHEMBL1883772 0.71 ABCG2 (0.62) ABCG2CYP1A1CYP1B1CYP1A2CYP2D6
SCHEMBL12002666 0.71 ABCG2 (0.45) ABCG2CYP1A1CYP1B1CYP1A2CYP2D6
SCHEMBL1879319 0.70 ABCG2 (0.69) ABCG2CYP1A1CYP1B1CYP1A2CYP2D6
SCHEMBL1879320 0.70 ABCG2 (0.69) ABCG2CYP1A1CYP1B1CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115243767-B Oil-in-water type emulsified cosmetic 花王株式会社 2024-07-16 CN disclosed
CN-113195060-B External preparation 花王株式会社 2024-04-30 CN disclosed
CN-113939265-B Method for inhibiting adhesion of atmospheric harmful substances 花王株式会社 2024-04-05 CN disclosed
CN-112955135-B Composition, sprayer and wiping cloth 富士胶片株式会社 2024-02-09 CN disclosed
CN-117042746-A External preparation for skin 花王株式会社 2023-11-10 CN disclosed
CN-116782870-A Film-forming composition 花王株式会社 2023-09-19 CN disclosed
CN-116490158-A Oil-in-water type emulsified cosmetic 花王株式会社 2023-07-25 CN disclosed
CN-113939265-A Method for inhibiting adhesion of harmful substances to atmosphere 花王株式会社 2022-01-14 CN disclosed