SCHEMBL4836334

SCHEMBL4836334

COc1ccc(C=CC(=O)OC(C)C)cc1.COc1ccc(C=CC(=O)OC([SiH3])(O[Si](C)(C)C)C(O[Si](C)(C)C)C(C)C)c(OC)c1OC

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 2/20 0.37
LMNA P02545 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
CA12 O43570 1/20 0.36
AKR1B10 O60218 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
AKR1B1 P15121 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
CYP1A1 P04798 3/20 0.36
CYP1B1 Q16678 3/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2D6 P10635 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
KDM4E B2RXH2 1/20 0.36
GLA P06280 1/20 0.36
MAPT P10636 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28693380 0.89 ABCG2 (0.46) ABCG2LMNACYP1A1CYP1B1CYP1A2
SCHEMBL4836339 0.79 ABCG2 (0.35) ABCG2LMNATDP1CA12AKR1B10
SCHEMBL6701256 0.78 KDM4E (0.45) ABCG2LMNACA1CA2CYP1A1
SCHEMBL1883771 0.74 ABCG2 (0.62) ABCG2LMNACA12AKR1B10CA1
SCHEMBL1883772 0.74 ABCG2 (0.62) ABCG2LMNACA12AKR1B10CA1
SCHEMBL3246989 0.73 ABCG2 (0.48) ABCG2LMNACYP1A1CYP1B1CYP1A2
SCHEMBL342878 0.70 CA12 (0.71) LMNATDP1CA12AKR1B10CA1
SCHEMBL15838 0.70 CA12 (0.71) LMNATDP1CA12AKR1B10CA1
Water SCHEMBL8001684 0.68 CA12 (0.69) LMNATDP1CA12AKR1B10CA1
Acetic Acid SCHEMBL28512748 0.66 CA12 (0.65) LMNATDP1CA12AKR1B10CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008032883-A2 COMPOSITION FOR THE PREPARATION OF COSMETICS, COSMETIC, AND METHOD FOR THE PREPARATION OF WATER-CONTAINING COSMETICS DOW CORNING TORAY CO., LTD. (JP) 2008-03-20 WO disclosed