SCHEMBL28694192

SCHEMBL28694192

Cc1ccc(-c2nc(-c3ccccc3)nc(=O)[nH]2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 2/20 0.61
NR1H3 Q13133 2/20 0.61
TNKS O95271 5/20 0.56
TNKS2 Q9H2K2 5/20 0.56
PARP1 P09874 4/20 0.56
GAA P10253 2/20 0.52
ALDH1A1 P00352 2/20 0.52
KDM4E B2RXH2 1/20 0.52
MEN1 O00255 1/20 0.52
GLA P06280 1/20 0.52
HPGD P15428 1/20 0.52
KMT2A Q03164 1/20 0.52
MAPT P10636 1/20 0.50
POLB P06746 1/20 0.49
NPC1 O15118 1/20 0.46
NFKB1 P19838 1/20 0.46
RAB9A P51151 1/20 0.46
NFKB2 Q00653 1/20 0.46
RELA Q04206 1/20 0.46
HPGDS O60760 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28677334 0.91 MAPT (0.53) NR1H2NR1H3TNKSTNKS2PARP1
SCHEMBL28675222 0.85 PARP1 (0.55) TNKSTNKS2PARP1GAAMEN1
SCHEMBL28682476 0.85 NR1H2 (0.59) NR1H2NR1H3TNKSTNKS2GAA
SCHEMBL28675746 0.85 NR1H2 (0.59) NR1H2NR1H3TNKSTNKS2PARP1
SCHEMBL28672620 0.85 TNKS (0.55) NR1H2NR1H3TNKSTNKS2PARP1
SCHEMBL28685099 0.83 GSK3B (0.56) GAAALDH1A1KDM4EHPGDMAPT
SCHEMBL28671719 0.83 NPC1 (0.59) TNKSTNKS2PARP1GAAALDH1A1
SCHEMBL28676032 0.81 TNKS (0.58) TNKSTNKS2PARP1HPGDRAB9A
SCHEMBL28671250 0.80 TNKS (0.59) TNKSTNKS2PARP1MEN1KMT2A
SCHEMBL23108627 0.78 L3MBTL1 (0.70) NR1H2NR1H3ALDH1A1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113173889-B Method for synthesizing 1,3, 5-triazine derivative 新乡市润宇新材料科技有限公司 2023-11-10 CN disclosed
CN-113173889-A Method for synthesizing 1,3, 5-triazine derivative 新乡市润宇新材料科技有限公司 2021-07-27 CN disclosed