Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | IL1RN | P18510 | 1/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5683553 | 0.85 | CYP2A6 (0.54) | CYP2A6CYP1A2CYP3A4CYP2C9CYP11B1 | |
| SCHEMBL20722627 | 0.81 | CYP2A6 (0.39) | CYP2A6CYP1A2CYP3A4CYP2C9CYP11B1 | |
| SCHEMBL16044934 | 0.81 | CYP2A6 (0.39) | CYP2A6CYP1A2CYP3A4CYP2C9CYP11B1 | |
| SCHEMBL7934672 | 0.78 | HTR2A (0.41) | KDM4EHTR2AHTR2CHTR2B | |
| SCHEMBL1662187 | 0.76 | CYP2A6 (0.52) | CYP2A6CYP1A2IL1RNERAP2ERAP1 | |
| SCHEMBL29385577 | 0.76 | CYP2A6 (0.52) | CYP2A6CYP1A2IL1RNERAP2ERAP1 | |
| SCHEMBL2675178 | 0.68 | CYP2A6 (0.38) | CYP2A6CYP3A4 | |
| SCHEMBL28088563 | 0.67 | CYP2A6 (0.55) | CYP2A6CYP1A2KDM4E | |
| SCHEMBL3478078 | 0.65 | ANPEP (0.49) | CYP2A6CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL30748444 | 0.65 | CYP2A6 (0.35) | CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975583-B1 | AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES | MERIAL LTD (US) | 2010-10-20 | — | — | EP | disclosed |
| US-6555709-B1 | Derivatives of 4-(naphth-2-ylmethyl)-N-(2-methylphenyl) benzamide; storing crops (cotton and rice); insecticides; miticides; nematocides; molluscs; anthelmintics; acarina; textiles; foods | HOECHST SCHERING AGREVO S.A. (FR) | 2003-04-29 | — | — | US | disclosed |
| EP-0975583-A1 | AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES | Hoechst Schering AgrEvo S.A. (FR) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998045252-A1 | AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES | HOECHST SCHERING AGREVO S.A. (FR) | 1998-10-15 | — | — | WO | disclosed |