Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 15/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.39 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | FECH | P22830 | 1/20 | 0.38 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.38 |
| ▸ | BMPR2 | Q13873 | 1/20 | 0.38 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.38 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.38 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.38 |
| ▸ | MAPKAP1 | Q9BPZ7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26791385 | 0.83 | TNK2 (0.47) | TNK2 | |
| SCHEMBL28626677 | 0.81 | TNK2 (0.43) | TNK2CSNK2A2CSNK2A1IGF1R | |
| SCHEMBL397549 | 0.80 | TNK2 (0.55) | TNK2CSNK2A2RIPK2RETNQO2 | |
| SCHEMBL25168436 | 0.80 | TNK2 (0.52) | TNK2CSNK2A2RIPK2RETNQO2 | |
| SCHEMBL31391188 | 0.80 | TNK2 (0.48) | TNK2CSNK2A2RIPK2RETNQO2 | |
| SCHEMBL28911444 | 0.80 | FGFR4 (0.49) | TNK2 | |
| SCHEMBL28911445 | 0.80 | FGFR4 (0.49) | TNK2 | |
| SCHEMBL593101 | 0.79 | TNK2 (0.51) | TNK2CSNK2A2RIPK2RETNQO2 | |
| SCHEMBL15929395 | 0.79 | TNK2 (0.48) | TNK2 | |
| SCHEMBL25273305 | 0.77 | PDE2A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114075190-A | Heterocyclic BTK inhibitors | 北京诺诚健华医药科技有限公司 | 2022-02-22 | — | — | CN | disclosed |