Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 14/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 4/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28628197 | 0.84 | TNK2 (0.48) | TNK2 | |
| SCHEMBL28628199 | 0.84 | TNK2 (0.48) | TNK2 | |
| SCHEMBL27188431 | 0.82 | TNK2 (0.34) | TNK2PDE2APDE3APDE3B | |
| SCHEMBL27188425 | 0.82 | TNK2 (0.34) | TNK2PDE2APDE3APDE3B | |
| SCHEMBL27188701 | 0.81 | TNK2 (0.35) | TNK2PDE2APDE3APDE3B | |
| SCHEMBL27188702 | 0.81 | TNK2 (0.35) | TNK2PDE2APDE3APDE3B | |
| SCHEMBL14488061 | 0.81 | PDE2A (0.45) | CSNK2A2CSNK2A1PDE2APDE3APDE3B | |
| SCHEMBL28694583 | 0.81 | TNK2 (0.43) | TNK2CSNK2A2CSNK2A1IGF1R | |
| SCHEMBL14488065 | 0.81 | PDE2A (0.45) | CSNK2A2CSNK2A1PDE2APDE3APDE3B | |
| SCHEMBL18283348 | 0.80 | TNK2 (0.48) | TNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113336760-B | Substituted amide derivatives, compositions and uses thereof | 深圳市塔吉瑞生物医药有限公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-113493439-B | Substituted acrylamide derivative, composition and application thereof | 深圳市塔吉瑞生物医药有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-113493439-A | Substituted acrylamide derivative, composition and application thereof | 深圳市塔吉瑞生物医药有限公司 | 2021-10-12 | — | — | CN | disclosed |
| CN-113336760-A | Substituted amide derivatives, compositions and uses thereof | 深圳市塔吉瑞生物医药有限公司 | 2021-09-03 | — | — | CN | disclosed |