Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.39 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29466052 | 1.00 | GSR (0.50) | GSRRAB9AKMT2AMEN1HTT | |
| SCHEMBL28695006 | 0.83 | RECQL (0.57) | GSRRAB9AKMT2AMEN1HTT | |
| SCHEMBL29466050 | 0.83 | RECQL (0.57) | GSRRAB9AKMT2AMEN1HTT | |
| SCHEMBL20383920 | 0.82 | GSR (0.48) | GSRRAB9AKMT2AMEN1HTT | |
| SCHEMBL12914311 | 0.82 | RAB9A (0.49) | GSRRAB9AKMT2AHTTKDM4E | |
| SCHEMBL28714311 | 0.81 | GSR (0.50) | GSRRAB9AKMT2AMEN1HTT | |
| SCHEMBL29466045 | 0.81 | GSR (0.50) | GSRRAB9AKMT2AMEN1HTT | |
| SCHEMBL16692229 | 0.80 | GSR (0.51) | GSRKMT2AMEN1HTTKDM4E | |
| SCHEMBL23933936 | 0.79 | GSR (0.51) | GSRRAB9AKMT2AMEN1HTT | |
| SCHEMBL12130058 | 0.79 | GSR (0.55) | GSRRAB9AKMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109206422-B | Bipolar compound based on 1,3, 4-thiadiazole and preparation method and application thereof | 湖北尚赛光电材料有限公司 | 2022-03-18 | — | — | CN | disclosed |