SCHEMBL2869595

SCHEMBL2869595

N#Cc1ccc(Cl)c(Cl)c1Cl

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 1/20 0.46
AR P10275 11/20 0.44
HTR2A P28223 1/20 0.42
HTR2C P28335 1/20 0.42
HTR2B P41595 1/20 0.42
MAOA P21397 2/20 0.41
MAOB P27338 2/20 0.41
CYP3A4 P08684 1/20 0.40
MAPK1 P28482 1/20 0.40
VCAM1 P19320 2/20 0.39
DYRK1A Q13627 1/20 0.35
CYP11B2 P19099 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31621318 0.89 AR (0.50) TRPV4ARHTR2AHTR2CHTR2B
SCHEMBL10733139 0.89 AR (0.50) TRPV4ARHTR2AHTR2CHTR2B
SCHEMBL10941730 0.82 TRPV4 (0.45) TRPV4ARHTR2AHTR2CHTR2B
SCHEMBL31038739 0.82 TRPV4 (0.45) TRPV4ARHTR2AHTR2CHTR2B
SCHEMBL27770780 0.82 TSHR (0.46) TRPV4MAOAMAOBCYP3A4MAPK1
SCHEMBL2555964 0.80 TRPV4 (0.43) TRPV4ARHTR2AHTR2CHTR2B
SCHEMBL3976812 0.78 AR (0.51) TRPV4AR
SCHEMBL10411218 0.78 TRPV4 (0.42) TRPV4ARHTR2AHTR2CHTR2B
SCHEMBL8859185 0.78 TRPV4 (0.42) TRPV4ARHTR2AHTR2CHTR2B
SCHEMBL1343670 0.78 AR (0.43) TRPV4ARHTR2AHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9039919-B2 Gel-type polymer electrolyte for dye-sensitized solar cell and dye-sensitized solar cell comprising the same Research & Business Foundation Sungkyunkwan University (KR) 2015-05-26 US claimed
US-20130330873-A1 GEL-TYPE POLYMER ELECTROLYTE FOR DYE-SENSITIZED SOLAR CELL AND DYE-SENSITIZED SOLAR CELL COMPRISING THE SAME Research & Business Foundation Sungkyunkwan University (KR) 2013-12-12 US claimed
US-8257871-B2 a mixture of cyclic esters, a nitrile-containing solvent and lithium salts, for use in rechargeable batteries, to improve swelling characteristics, discharge capacity characteristics at low temperatures and durability SAMSUNG SDI CO., LTD. (KR) 2012-09-04 US claimed
US-7718322-B2 Electrolyte for rechargeable lithium battery and rechargeable lithium battery comprising same SAMSUNG SDI CO., LTD. (KR) 2010-05-18 US claimed
US-20080131785-A1 Electrolyte for lithium secondary battery and lithium secondary battery including the same SAMSUNG SDI CO., LTD., A CORPORATION CHARTERED IN AND EXISTING UNDER THE LAWS OF THE REPUBLIC OF KOREA (KR) 2008-06-05 US claimed
EP-1508934-B1 Electrolyte for rechargeable lithium battery and rechargeable lithium battery comprising the same SAMSUNG SDI CO LTD (KR) 2007-02-28 EP claimed
US-20050084765-A1 Electrolyte for rechargeable lithium battery and rechargeable lithium battery comprising same SAMSUNG SDI CO., LTD. (KR) 2005-04-21 US claimed
EP-1508934-A1 Electrolyte for rechargeable lithium battery and rechargeable lithium battery comprising the same Samsung SDI Co., Ltd. (KR) 2005-02-23 EP claimed
EP-0635486-B1 Process for the preparation of fluorobenzonitriles CLARIANT GMBH (DE) 1998-12-09 EP claimed
US-5466859-A Process for preparing fluorobenzonitriles HOECHST AKTIENGESELLSCHAFT (DE) 1995-11-14 US claimed
EP-0441004-B1 Process for preparing aromatic nitriles ENICHEM SINTESI (IT) 1995-09-06 EP claimed
EP-0635486-A2 Process for the preparation of fluorobenzonitriles HOECHST AKTIENGESELLSCHAFT (DE) 1995-01-25 EP claimed
EP-0441004-A1 Process for preparing aromatic nitriles ENICHEM SYNTHESIS S.p.A. (IT) 1991-08-14 EP claimed
JP-58038248-A None JP disclosed
JP-4321644-A None JP disclosed
US-20250242338-A1 IRON PHOSPHIDE NANOPARTICLES, AND COMPOSITE BODY AND REDUCTION CATALYST EACH CONTAINING SAME OSAKA UNIVERSITY (JP) 2025-07-31 US disclosed
EP-0635486-A2 Process for the preparation of fluorobenzonitriles HOECHST AKTIENGESELLSCHAFT (DE) 1995-01-25 EP disclosed
JP-H04321644-A PRODUCTION OF 2,4,5-TRIFLUOROBENZOIC ACID ASAHI GLASS CO LTD 1992-11-11 JP disclosed
EP-0441004-A1 Process for preparing aromatic nitriles ENICHEM SYNTHESIS S.p.A. (IT) 1991-08-14 EP disclosed
JP-S5838248-A 3-CHLORO-2,6-DIFLUOROBENZONITRILE ISHIHARA SANGYO KAISHA LTD 1983-03-05 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250242338-A1 IRON PHOSPHIDE NANOPARTICLES, AND COMPOSITE BODY AND REDUCTION CATALYST EACH CONTAINING SAME FECH, PI4K2A, PHOSPHO1 TRPV4 1443/4885AR 4125/4885HTR2A 4255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.