SCHEMBL28696136

SCHEMBL28696136

CCc1ccc(C(=O)OOP(=O)(O)Oc2ccc(C(C)C)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.47
CYP2C19 P33261 2/20 0.47
ALDH1A1 P00352 5/20 0.44
RAB9A P51151 4/20 0.44
NPC1 O15118 3/20 0.44
RXRA P19793 2/20 0.44
RXRB P28702 2/20 0.44
LMNA P02545 2/20 0.40
PRSS1 P07477 1/20 0.39
ACR P10323 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
BLM P54132 1/20 0.38
PLK1 P53350 1/20 0.37
KDM4E B2RXH2 2/20 0.36
POLB P06746 1/20 0.36
CYP2C9 P11712 1/20 0.36
USP2 O75604 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28673145 0.92 PRSS1 (0.44) SMN1; SMN2ALDH1A1RAB9ANPC1RXRA
SCHEMBL28689664 0.90 SMN1; SMN2 (0.43) SMN1; SMN2ALDH1A1RAB9ANPC1RXRA
SCHEMBL29165639 0.89 SMN1; SMN2 (0.45) SMN1; SMN2CYP2C19ALDH1A1RAB9ANPC1
SCHEMBL28697487 0.88 PRSS1 (0.41) SMN1; SMN2ALDH1A1RAB9ANPC1RXRA
SCHEMBL28931874 0.88 PRSS1 (0.41) SMN1; SMN2ALDH1A1RAB9ANPC1RXRA
SCHEMBL29017985 0.87 SMN1; SMN2 (0.49) SMN1; SMN2CYP2C19ALDH1A1RAB9ANPC1
SCHEMBL28672554 0.87 CYP2C19 (0.51) SMN1; SMN2CYP2C19ALDH1A1RXRARXRB
SCHEMBL28687011 0.86 HPGD (0.43) ALDH1A1RAB9ANPC1RXRARXRB
SCHEMBL29017966 0.84 MAPT (0.41) SMN1; SMN2ALDH1A1RAB9ANPC1LMNA
SCHEMBL28931711 0.78 CES2 (0.39) SMN1; SMN2ALDH1A1RAB9ANPC1RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114085301-A Solid catalyst component for preparing olefin polymer and application thereof 中国石油化工股份有限公司 2022-02-25 CN claimed
CN-113929797-A Solid catalyst component and catalyst system for producing polymers 中国石油化工股份有限公司 2022-01-14 CN claimed
CN-113929798-A Solid catalyst component and catalyst system for olefin polymerization 中国石油化工股份有限公司 2022-01-14 CN claimed
CN-113929799-A Catalyst component for olefin polymerization, catalyst system and application 中国石油化工股份有限公司 2022-01-14 CN claimed
CN-114085301-A Solid catalyst component for preparing olefin polymer and application thereof 中国石油化工股份有限公司 2022-02-25 CN disclosed
CN-113929797-A Solid catalyst component and catalyst system for producing polymers 中国石油化工股份有限公司 2022-01-14 CN disclosed
CN-113929798-A Solid catalyst component and catalyst system for olefin polymerization 中国石油化工股份有限公司 2022-01-14 CN disclosed
CN-113929799-A Catalyst component for olefin polymerization, catalyst system and application 中国石油化工股份有限公司 2022-01-14 CN disclosed