Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 2/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9495545 | 0.90 | HTR2C (0.54) | HTR2CHTR2AHTR2BGRM7MAP3K14 | |
| SCHEMBL14849672 | 0.86 | HTR2C (0.49) | HTR2CHTR2AHTR2BPDE10A | |
| SCHEMBL6386133 | 0.80 | HTR2C (0.69) | HTR2CHTR2AHTR2BGRM7 | |
| SCHEMBL26530978 | 0.79 | HTR2C (0.62) | HTR2CHTR2AHTR2BPDE10A | |
| SCHEMBL1128139 | 0.78 | HTR2C (0.67) | HTR2CHTR2AHTR2B | |
| SCHEMBL30603834 | 0.78 | HTR2C (0.67) | HTR2CHTR2AHTR2B | |
| SCHEMBL16956125 | 0.76 | HTR2C (0.74) | HTR2CHTR2AHTR2BGRM7 | |
| SCHEMBL28452283 | 0.75 | HTR2C (0.52) | HTR2CHTR2AHTR2BPDE10A | |
| SCHEMBL15517656 | 0.73 | ALDH1A1 (0.42) | HTR2CMAP3K14PDE10A | |
| SCHEMBL31546566 | 0.73 | CD44 (0.38) | HTR2CHTR2AHTR2BMAP3K14PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111440132-B | Novel method for preparing oxygen heterocyclic compound by ionic liquid catalysis | 中国科学院化学研究所 | 2022-02-01 | — | — | CN | claimed |