Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Methacrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL6862647 | 0.97 | TDP1 (0.42) | TDP1CA5ACA5BHSD17B10FFAR3 | |
| Methacrylic Acid SCHEMBL999438 | 0.97 | TDP1 (0.42) | TDP1CA5ACA5BHSD17B10FFAR3 | |
| Methacrylic Acid SCHEMBL28074051 | 0.94 | TDP1 (0.40) | TDP1CA5ACA5BHSD17B10FFAR3 | |
| Methacrylic Acid SCHEMBL28285493 | 0.94 | TDP1 (0.40) | TDP1CA5ACA5BHSD17B10FFAR3 | |
| Methacrylic Acid SCHEMBL22493124 | 0.94 | TDP1 (0.40) | TDP1CA5ACA5BHSD17B10FFAR3 | |
| Methacrylic Acid SCHEMBL11177420 | 0.94 | TDP1 (0.40) | TDP1CA5ACA5BHSD17B10FFAR3 | |
| Methacrylic Acid SCHEMBL28293735 | 0.94 | TDP1 (0.40) | TDP1CA5ACA5BHSD17B10FFAR3 | |
| Methacrylic Acid SCHEMBL1275317 | 0.94 | TDP1 (0.40) | TDP1CA5ACA5BHSD17B10FFAR3 | |
| Methacrylic Acid SCHEMBL11406486 | 0.88 | TDP1 (0.36) | TDP1CA5ACA5BHSD17B10FFAR3 | |
| Methacrylic Acid SCHEMBL11406490 | 0.88 | TDP1 (0.36) | TDP1CA5ACA5BHSD17B10FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114085446-A | Creep-resistant composite material and preparation method thereof | 四川大学 | 2022-02-25 | — | — | CN | disclosed |