Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.51 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29442794 | 1.00 | LMNA (0.61) | LMNATDP1CYP19A1SOS1HTT | |
| SCHEMBL2027987 | 0.81 | LMNA (0.61) | LMNATDP1CYP19A1HTTALDH1A1 | |
| SCHEMBL2038332 | 0.81 | LMNA (0.61) | LMNATDP1CYP19A1HTTALDH1A1 | |
| SCHEMBL4345160 | 0.80 | SOS1 (0.65) | SOS1HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL11545629 | 0.80 | LMNA (0.75) | LMNATDP1CYP19A1HTTALDH1A1 | |
| SCHEMBL14662201 | 0.79 | SOS1 (0.60) | SOS1EGFRFFAR4 | |
| SCHEMBL11552476 | 0.79 | TDP1 (0.62) | LMNATDP1CYP19A1HTTKMT2A | |
| SCHEMBL17062366 | 0.78 | LMNA (0.66) | LMNATDP1CYP19A1HTTKMT2A | |
| SCHEMBL12260750 | 0.77 | LMNA (0.61) | LMNATDP1CYP19A1HTTALDH1A1 | |
| SCHEMBL12330285 | 0.77 | LMNA (0.61) | LMNATDP1CYP19A1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174273-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2022-03-11 | — | — | CN | disclosed |