SCHEMBL28697224

SCHEMBL28697224

CCCCCCCC(CC)(C(=O)OC)C(=O)OC

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.46
MAPT P10636 1/20 0.46
KMT2A Q03164 1/20 0.46
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
EPHX1 P07099 1/20 0.44
CES2 O00748 1/20 0.42
GGPS1 O95749 6/20 0.41
USP2 O75604 1/20 0.41
LMNA P02545 1/20 0.41
SMPD1 P17405 1/20 0.40
ZDHHC7 Q9NXF8 1/20 0.40
FDPS P14324 8/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28935350 0.98 MEN1 (0.43) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL7106303 0.94 MEN1 (0.47) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL7543083 0.94 MEN1 (0.47) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL25173893 0.94 MEN1 (0.47) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL486917 0.94 MEN1 (0.47) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL23859895 0.94 MEN1 (0.47) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL21679731 0.92 MEN1 (0.46) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL21679729 0.92 MEN1 (0.46) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL21679706 0.92 MEN1 (0.46) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL21679707 0.92 MEN1 (0.46) MEN1MAPTKMT2AATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114174263-A Non-lysosomal glucosylceramidase inhibitors and uses thereof 阿勒克图治疗公司 2022-03-11 CN disclosed