SCHEMBL486917

SCHEMBL486917

CCCCCCCCC(CCCCCCCC)(C(=O)OC)C(=O)OC

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.47
MAPT P10636 1/20 0.47
KMT2A Q03164 1/20 0.47
ATM Q13315 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
EPHX1 P07099 1/20 0.45
CES2 O00748 1/20 0.44
GGPS1 O95749 6/20 0.42
USP2 O75604 1/20 0.41
LMNA P02545 1/20 0.41
SMPD1 P17405 1/20 0.41
ZDHHC7 Q9NXF8 1/20 0.41
FDPS P14324 8/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7106303 1.00 MEN1 (0.47) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL23859895 1.00 MEN1 (0.47) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL7543083 1.00 MEN1 (0.47) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL25173893 1.00 MEN1 (0.47) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL21679706 0.98 MEN1 (0.46) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL21679707 0.98 MEN1 (0.46) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL21679731 0.98 MEN1 (0.46) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL21679729 0.98 MEN1 (0.46) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL25200704 0.98 MEN1 (0.44) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL28697224 0.94 MEN1 (0.46) MEN1MAPTKMT2AATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137629-A1 Novel Lipids For Delivery Of Nucleic Acid Segments ASTRAZENECA AB (SE) 2026-05-21 US disclosed
EP-4423095-A1 NOVEL LIPIDS FOR DELIVERY OF NUCLEIC ACID SEGMENTS AstraZeneca AB (SE) 2024-09-04 EP disclosed
CN-118119627-A Novel lipids for delivery of nucleic acid segments 阿斯利康(瑞典)有限公司 2024-05-31 CN disclosed
US-20230348362-A1 LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS Suzhou Abogen Biosciences Co., Ltd. (CN) 2023-11-02 US disclosed
US-20230233468-A1 LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS Suzhou Abogen Biosciences Co., Ltd. (CN) 2023-07-27 US disclosed
WO-2023125889-A1 QUADRIVALENT MRNA VACCINES FOR INFLUENZA VIRUSES Suzhou Abogen Biosciences Co., Ltd. (CN) 2023-07-06 WO disclosed
WO-2023098842-A1 NUCLEIC ACID VACCINES FOR CORONAVIRUS BASED ON SEQUENCES DERIVED FROM SARS-CoV-2 OMICRON STRAIN Suzhou Abogen Biosciences Co., Ltd. (CN) 2023-06-08 WO disclosed
US-20230151049-A1 Compounds Useful in HIV Therapy VIIV HEALTHCARE COMPANY (US) 2023-05-18 US disclosed
US-20230151049-A1 Compounds Useful in HIV Therapy VIIV HEALTHCARE COMPANY (US) 2023-05-18 US disclosed
WO-2023073534-A1 NOVEL LIPIDS FOR DELIVERY OF NUCLEIC ACID SEGMENTS ASTRAZENECA AB (SE) 2023-05-04 WO disclosed
EP-4126888-A1 COMPOUNDS USEFUL IN HIV THERAPY VIIV Healthcare Company (US) 2023-02-08 EP disclosed
CN-115304481-A Preparation method of dimethyl dialkyl malonate 九江德思光电材料有限公司 2022-11-08 CN disclosed
WO-2021194828-A1 COMPOUNDS USEFUL IN HIV THERAPY VIIV HEALTHCARE COMPANY (US) 2021-09-30 WO disclosed
EP-1178031-B1 PROCESS FOR THE PREPARATION OF ORGANIC COMPOUNDS WITH MANGANESE CATALYSTS OR THE LIKE DAICEL CHEM (JP) 2012-02-01 EP disclosed
US-6548713-B2 Efficiently producing a compound having an alkyl group or alkenyl group bonded at the alpha position of an electron attractive group, by catalytic radical addition reaction with compound of Group 5,6,7,8, or 9 DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2003-04-15 US disclosed
US-20020165416-A1 Process for the preparation of organic compounds with manganese cataylsts or the like DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-11-07 US disclosed
EP-1178031-A1 PROCESS FOR THE PREPARATION OF ORGANIC COMPOUNDS WITH MANGANESE CATALYSTS OR THE LIKE Daicel Chemical Industries, Ltd. (JP) 2002-02-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260137629-A1 Novel Lipids For Delivery Of Nucleic Acid Segments LDLR, NPC1, NSUN2 MEN1 3805/4885MAPT 1579/4885KMT2A 1911/4885
US-20230233468-A1 LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS CETP, NPC1, LCAT MEN1 1909/4885MAPT 359/4885KMT2A 1910/4885
US-20230151049-A1 Compounds Useful in HIV Therapy CCR5, CD4, NPC1 MEN1 3503/4885MAPT 1067/4885KMT2A 3565/4885
US-20230348362-A1 LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS CETP, NPC1, LCAT MEN1 1909/4885MAPT 359/4885KMT2A 1910/4885
US-20020165416-A1 Process for the preparation of organic compounds with manganese cataylsts or the like SOD1, CAT, SOD3 MEN1 4065/4885MAPT 2030/4885KMT2A 1383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.