Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22566290 | 1.00 | CHRM2 (0.38) | CHRM2CHRM1CHRM3CYP1A2CYP2D6 | |
| SCHEMBL22566349 | 0.81 | KMT2A (0.47) | CHRM2CHRM1CHRM3CYP1A2CYP2D6 | |
| SCHEMBL28693167 | 0.81 | KMT2A (0.47) | CHRM2CHRM1CHRM3CYP1A2CYP2D6 | |
| SCHEMBL3812105 | 0.79 | CYP1A2 (0.46) | CHRM2CHRM1CHRM3CYP1A2CYP2D6 | |
| SCHEMBL8868519 | 0.79 | CYP1A2 (0.46) | CHRM2CHRM1CHRM3CYP1A2CYP2D6 | |
| SCHEMBL8868505 | 0.79 | CYP1A2 (0.46) | CHRM2CHRM1CHRM3CYP1A2CYP2D6 | |
| SCHEMBL30071649 | 0.79 | LMNA (0.48) | MAPTMEN1KMT2ALMNATSHR | |
| SCHEMBL30375691 | 0.78 | CHRM2 (0.40) | CHRM2CHRM1CHRM3CYP1A2CYP2D6 | |
| SCHEMBL22556019 | 0.77 | CYP2D6 (0.38) | CHRM2CHRM1CHRM3CYP1A2CYP2D6 | |
| SCHEMBL3624082 | 0.74 | CYP3A4 (0.45) | CHRM2CHRM1CHRM3CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114025759-A | Compounds and methods for treating ocular diseases | 阿祖拉眼科有限公司 | 2022-02-08 | — | — | CN | disclosed |