Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SLC5A1 | P13866 | 3/20 | 0.44 |
| ▸ | SLC5A2 | P31639 | 3/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SPR | P35270 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29408091 | 1.00 | TP53 (0.57) | TP53ALOX12MAPTSMN1; SMN2KMT2A | |
| SCHEMBL28686848 | 0.87 | TP53 (0.57) | TP53ALOX12MAPTSMN1; SMN2KMT2A | |
| SCHEMBL29408088 | 0.87 | TP53 (0.57) | TP53ALOX12MAPTSMN1; SMN2KMT2A | |
| SCHEMBL3400622 | 0.85 | TP53 (0.66) | TP53ALOX12MAPTSMN1; SMN2KMT2A | |
| SCHEMBL29408102 | 0.81 | NOTUM (0.51) | TP53MAPTALDH1A1PTGS2MET | |
| SCHEMBL28685562 | 0.81 | NOTUM (0.51) | TP53MAPTALDH1A1PTGS2MET | |
| SCHEMBL29408101 | 0.81 | NOTUM (0.51) | TP53MAPTALDH1A1PTGS2MET | |
| SCHEMBL3406655 | 0.80 | POLB (0.62) | TP53ALOX12MAPTSMN1; SMN2KMT2A | |
| SCHEMBL28697962 | 0.79 | KCNN4 (0.36) | TP53MAPTKMT2AALDH1A1HPGD | |
| SCHEMBL29408072 | 0.79 | KCNN4 (0.36) | TP53MAPTKMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114127066-A | Inhibitors of indoleamine 2, 3-dioxygenase and/or tryptophan 2, 3-dioxygenase | 爱杜西亚药品有限公司 | 2022-03-01 | — | — | CN | disclosed |