SCHEMBL2869853

SCHEMBL2869853

CN(C)C(=O)NC1CCCCC1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 6/20 0.56
NPC1 O15118 3/20 0.56
RAB9A P51151 3/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
MAPT P10636 1/20 0.56
KDM4E B2RXH2 1/20 0.56
ALDH1A1 P00352 1/20 0.56
CYP3A4 P08684 1/20 0.56
EPHX2 P34913 1/20 0.56
PKM P14618 1/20 0.56
HPGD P15428 1/20 0.50
ADRA2A P08913 1/20 0.49
PDE4A P27815 1/20 0.49
ADRA1A P35348 1/20 0.49
NPSR1 Q6W5P4 1/20 0.47
MMP2 P08253 3/20 0.47
CA12 O43570 2/20 0.47
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
CA9 Q16790 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9451038 1.00 EPHX1 (0.56) EPHX1NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL135838 1.00 EPHX1 (0.56) EPHX1NPC1RAB9ASMN1; SMN2MAPT
Hydrochloric Acid SCHEMBL3720424 0.98 PKM (0.54) EPHX1NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL11438411 0.98 PKM (0.53) EPHX1NPC1RAB9ASMN1; SMN2MAPT
Maleic Acid SCHEMBL31296596 0.89 NPC1 (0.62) EPHX1NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL20377850 0.88 CA1 (0.45) EPHX1SMN1; SMN2ALDH1A1EPHX2PKM
SCHEMBL18380886 0.88 CA1 (0.45) EPHX1SMN1; SMN2ALDH1A1EPHX2PKM
SCHEMBL2051051 0.88
SCHEMBL11608613 0.86 EPHX1 (0.56) EPHX1NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL14557545 0.84 PKM (0.54) EPHX1NPC1RAB9ASMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111712486-A Novel crystal form of cariprazine hydrochloride, preparation method and application thereof 上海诚妙医药科技有限公司 2020-09-25 CN claimed
WO-2020056929-A1 NEW CARIPRAZINE HYDROCHLORIDE CRYSTAL FORM AND PREPARATION METHOD AND APPLICATION OF NEW CARIPRAZINE HYDROCHLORIDE CRYSTAL FORM 上海诚妙医药科技有限公司 2020-03-26 WO claimed
EP-2185155-B1 PHARMACEUTICAL COMPOSITIONS CONTAINING DOPAMINE RECEPTOR LIGANDS AND METHODS OF TREATMENT USING DOPAMINE RECPTOR LIGANDS RICHTER GEDEON NYRT (HU) 2017-10-04 EP claimed
CN-104496854-B Dimethyl carbamide compounds of 3 cyclohexyl 1,1 and its preparation method and application 上海医药工业研究院 2017-09-22 CN claimed
CN-105193807-A PHARMACEUTICAL COMPOSITIONS AND METHOD FOR TREATING ACUTE MANIA RICHTER GEDEON NYRT 2015-12-30 CN claimed
EP-2925324-A1 TRANS-4-{2-[4-(2,3-DICHLOROPHENYL)-PIPERAZIN-1-YL]-ETHYL}-N,N-DIMETHYLCARBAMOYL-CYCLOHEXYLAMINE FOR TREATING NEGATIVE SYMPTOMS OF SCHIZOPHRENIA Richter Gedeon Nyrt. (HU) 2015-10-07 EP claimed
CN-104546852-A (THIO) -CARBAMOYL-CYCLOHEXANE DERIVATIVES AND METHOD FOR TREATING SCHIZOPHRENIA RICHTER GEDEON NYRT 2015-04-29 CN claimed
CN-104496854-A 3-cyclohexyl-1,1-dimethylurea compound as well as preparation method and application thereof SHANGHAI INST PHARM INDUSTRY 2015-04-08 CN claimed
WO-2014083522-A1 TRANS-4-{2-[4-(2,3-DICHLOROPHENYL)-PIPERAZIN-1-YL]-ETHYL}-N,N-DIMETHYLCARBAMOYL-CYCLOHEXYLAMINE FOR TREATING NEGATIVE SYMPTOMS OF SCHIZOPHRENIA RICHTER GEDEON NYRT. (HU) 2014-06-05 WO claimed
EP-3971920-B1 RESIN COMPOSITION AJINOMOTO KK (JP) 2026-04-01 EP disclosed
EP-4679461-A2 RESIN COMPOSITION AND PRODUCTION METHOD OF THE SAME AJINOMOTO CO., INC. (JP) 2026-01-14 EP disclosed
EP-4586285-A1 RESIN COMPOSITION AJINOMOTO CO., INC. (JP) 2025-07-16 EP disclosed
CN-120192630-A Resin composition 味之素株式会社 2025-06-24 CN disclosed
CN-120192629-A Resin composition 味之素株式会社 2025-06-24 CN disclosed
EP-0361852-A2 Water dispersible polymers for coatings NORTH DAKOTA STATE UNIVERSITY (US) 1990-04-04 EP disclosed
EP-0361853-A2 Mesogens and polymers with mesogens NORTH DAKOTA STATE UNIVERSITY (US) 1990-04-04 EP disclosed
US-4282135-A Aminoplast dispersions and polyurethanes prepared therefrom BAYER AKTIENGESELLSCHAFT (DE) 1981-08-04 US disclosed
US-4240954-A CYCLOHEXYL UREAS OR THIOUREAS AMERICAN CYANAMID COMPANY (US) 1980-12-23 US disclosed
US-4225481-A Aminoplast dispersions and polyurethanes prepared therefrom BAYER AKTIENGESELLSCHAFT (DE) 1980-09-30 US disclosed
US-4122049-A Process for the production of polyurethane foam BAYER AKTIENGESELLSCHAFT (DE) 1978-10-24 US disclosed