SCHEMBL28699073

SCHEMBL28699073

O=C(Cc1ccc(C(=O)O)c(C(=O)O)c1)OC(=O)Cc1ccc(C(=O)O)c(C(=O)O)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KLKB1 P03952 1/20 0.44
CTSB P07858 1/20 0.44
MMP9 P14780 1/20 0.44
DNMT1 P26358 1/20 0.44
DNMT3B Q9UBC3 1/20 0.44
DNMT3L Q9UJW3 1/20 0.44
DNMT3A Q9Y6K1 1/20 0.44
ALDH1A1 P00352 5/20 0.43
CDC25B P30305 2/20 0.43
CASP6 P55212 1/20 0.43
RCE1 Q9Y256 1/20 0.43
FOLH1 Q04609 3/20 0.41
CFD P00746 1/20 0.41
LCK P06239 1/20 0.41
HNF4A P41235 1/20 0.40
USP2 O75604 1/20 0.39
TP53 P04637 1/20 0.39
HSD17B10 Q99714 3/20 0.39
CDC25A P30304 1/20 0.39
ALOX15 P16050 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28699074 0.90 CFD (0.47) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL7562901 0.82 KDM4E (0.55) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL7852526 0.78 CFD (0.46) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL28222381 0.78 CFD (0.46) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL2857663 0.78 KLKB1 (0.48) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL29365057 0.77 KLKB1 (0.69) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL29404777 0.77 LCK (0.62) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL21621 0.77 KLKB1 (0.69) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL23103 0.77 LCK (0.62) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL21277589 0.76 KLKB1 (0.47) KLKB1CTSBMMP9DNMT1DNMT3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110023369-B Process for preparing TDI based polyurethane flexible foams containing organic acid anhydrides and/or organic acid chlorides 科思创德国股份有限公司 2022-03-18 CN disclosed