Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22991886 | 0.98 | HPGD (0.51) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1901176 | 0.98 | HPGD (0.51) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL17761666 | 0.98 | HPGD (0.51) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL192227 | 0.89 | MEN1 (0.58) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5553211 | 0.89 | MEN1 (0.58) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2789282 | 0.89 | MEN1 (0.58) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL427670 | 0.89 | HPGD (0.58) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL16041071 | 0.88 | HPGD (0.55) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1903973 | 0.85 | NR1H2 (0.50) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL4524244 | 0.84 | HPGD (0.49) | HPGDALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113382986-A | Tyrosine kinase inhibitor compositions, methods of making and methods of using the same | 黑钻治疗公司 | 2021-09-10 | — | — | CN | disclosed |