Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1901176 | 1.00 | HPGD (0.51) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL17761666 | 1.00 | HPGD (0.51) | HPGDALDH1A1MAPTMEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL28699367 | 0.98 | HPGD (0.50) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5553211 | 0.91 | MEN1 (0.58) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL192227 | 0.91 | MEN1 (0.58) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2789282 | 0.91 | MEN1 (0.58) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL427670 | 0.90 | HPGD (0.58) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL16041071 | 0.89 | HPGD (0.55) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1903973 | 0.86 | NR1H2 (0.50) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL4524244 | 0.85 | HPGD (0.49) | HPGDALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12544359-B2 | 1-aminosulfonyl-2-carboxypyrrole derivatives as metallo-beta-lactamase inhibitors | Infex Therapeutics Limited (GB) | 2026-02-10 | — | — | US | disclosed |
| CN-119100967-A | 1-Aminosulfonyl-2-carboxypyrrole derivatives as metallo-beta-lactamase inhibitors | 英菲克斯治疗有限公司 | 2024-12-10 | — | — | CN | disclosed |
| CN-114728902-B | 1-Aminosulfonyl-2-carboxypyrrole derivatives as metallo-beta-lactamase inhibitors | 英菲克斯治疗有限公司 | 2024-09-13 | — | — | CN | disclosed |
| US-20230018460-A1 | 1-AMINOSULFONYL-2-CARBOXYPYRROLE DERIVATIVES AS METALLO-BETA-LACTAMASE INHIBITORS | Infex Therapeutics Limited (GB) | 2023-01-19 | — | — | US | disclosed |
| US-20230018460-A1 | 1-AMINOSULFONYL-2-CARBOXYPYRROLE DERIVATIVES AS METALLO-BETA-LACTAMASE INHIBITORS | Infex Therapeutics Limited (GB) | 2023-01-19 | — | — | US | disclosed |
| EP-4061800-A1 | 1-AMINOSULFONYL-2-CARBOXYPYRROLE DERIVATIVES AS METALLO-BETA-LACTAMASE INHIBITORS | Infex Therapeutics Limited (GB) | 2022-09-28 | — | — | EP | disclosed |
| CN-114728902-A | 1-aminosulfonyl-2-carboxypyrrole derivatives as metallo-beta-lactamase inhibitors | 英菲克斯治疗有限公司 | 2022-07-08 | — | — | CN | disclosed |
| WO-2021099793-A1 | 1-AMINOSULFONYL-2-CARBOXYPYRROLE DERIVATIVES AS METALLO-BETA-LACTAMASE INHIBITORS | Infex Therapeutics Limited (GB) | 2021-05-27 | — | — | WO | disclosed |
| WO-2021030711-A1 | ALKYNYL QUINAZOLINE COMPOUNDS | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2021-02-18 | — | — | WO | disclosed |
| CN-1138773-C | 4-alkenyl (and alkynyl) oxindoles as inhibitors of cell cycle protein dependent kinases, in particular CDK2 | - | 2004-02-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12544359-B2 | 1-aminosulfonyl-2-carboxypyrrole derivatives as metallo-beta-lactamase inhibitors | CBR1, CBR3, SRR | HPGD 2168/4885ALDH1A1 676/4885MAPT 4855/4885 |
| US-20230018460-A1 | 1-AMINOSULFONYL-2-CARBOXYPYRROLE DERIVATIVES AS METALLO-BETA-LACTAMASE INHIBITORS | CPN1, CMBL, ALDH7A1 | HPGD 900/4885ALDH1A1 143/4885MAPT 4616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.