SCHEMBL28699405

SCHEMBL28699405

O=C(Oc1c(CN2CCN(C(=O)OC(C(F)(F)F)C(F)(F)F)CC2)cccc1C(F)(F)F)C1CC1

nearest known ligand 0.68

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 20/20 0.68
ABHD6 Q9BV23 7/20 0.55
PLA2G7 Q13093 6/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20137091 0.89 MGLL (0.67) MGLLABHD6PLA2G7
SCHEMBL20137020 0.81 MGLL (1.00) MGLLABHD6PLA2G7
SCHEMBL21571689 0.81 MGLL (0.81) MGLL
SCHEMBL19992938 0.79 MGLL (0.61) MGLLABHD6PLA2G7
SCHEMBL20158285 0.79 MGLL (0.77) MGLLABHD6PLA2G7
SCHEMBL20136924 0.79 MGLL (1.00) MGLL
SCHEMBL28696644 0.79 MGLL (0.72) MGLLABHD6PLA2G7
SCHEMBL18064784 0.78 MGLL (0.62) MGLLABHD6PLA2G7
SCHEMBL20137036 0.78 MGLL (0.68) MGLLABHD6PLA2G7
SCHEMBL20137029 0.77 MGLL (0.79) MGLLABHD6PLA2G7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110267963-B MAGL inhibitors H.隆德贝克有限公司 2022-04-01 CN disclosed