Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 6/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4224125 | 0.88 | USP2 (0.44) | RORCUSP2SMN1; SMN2CYP11B2USP30 | |
| SCHEMBL350339 | 0.84 | USP2 (0.46) | RORCUSP2SMN1; SMN2CYP11B2USP30 | |
| SCHEMBL21949407 | 0.81 | USP2 (0.50) | USP2SMN1; SMN2HPGDTACR1EPHX2 | |
| SCHEMBL2706445 | 0.81 | USP2 (0.50) | USP2SMN1; SMN2HPGDTACR1EPHX2 | |
| SCHEMBL2593157 | 0.79 | HPGD (0.42) | RORCUSP2SMN1; SMN2CYP11B2USP30 | |
| SCHEMBL351164 | 0.78 | USP2 (0.41) | RORCUSP2SMN1; SMN2CYP11B2USP30 | |
| SCHEMBL29023689 | 0.77 | USP2 (0.49) | RORCUSP2SMN1; SMN2CYP11B2USP30 | |
| SCHEMBL3506743 | 0.77 | USP2 (0.44) | RORCUSP2SMN1; SMN2HPGDEPHX2 | |
| SCHEMBL1061211 | 0.76 | USP2 (0.45) | RORCUSP2SMN1; SMN2CYP11B2USP30 | |
| SCHEMBL29359057 | 0.76 | LMNA (0.46) | RORCSMN1; SMN2HPGDEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3941922-A1 | INHIBITORS OF RAF KINASES | Kinnate Biopharma Inc. (US) | 2022-01-26 | — | — | EP | disclosed |
| CN-113874381-A | Inhibitors of RAF kinase | 金耐特生物制药公司 | 2021-12-31 | — | — | CN | disclosed |